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Dual inhibition of EGFR, VEGF improves progression-free survival in NSCLC

26 Mar 2023

Inhibiting the pathways of both epidermal growth factor receptor (EGFR) and vascular endothelial growth factor (VEGF) leads to significant improvements in progression-free survival (PFS) but more adverse events (AEs), results of a meta-analysis have shown.

Dual inhibition of EGFR, VEGF improves progression-free survival in NSCLC

26 Mar 2023

Maternal Crohn’s disease ups risk of infection in offspring

26 Mar 2023

Offspring born to mothers with Crohn’s disease (CD), but not ulcerative colitis, are at higher risk of infection, suggests a study. This association is partly mediated by adverse birth outcomes and antitumour necrosis factor α (anti-TNFα) agents.

Maternal Crohn’s disease ups risk of infection in offspring

26 Mar 2023

$Add-on pembrolizumab helps improve outcomes of relapsed, refractory Hodgkin lymphoma$

Add-on pembrolizumab helps improve outcomes of relapsed, refractory Hodgkin lymphoma

25 Mar 2023

Adding pembrolizumab to chemotherapy consisting of ifosfamide, carboplatin, and etoposide (ICE) in the treatment of patients with relapsed or refractory classic Hodgkin lymphoma appears to be well tolerated and associated with better outcomes in comparison with reports from studies on chemotherapy-only regimens, according to data from a phase II study.

Add-on pembrolizumab helps improve outcomes of relapsed, refractory Hodgkin lymphoma

25 Mar 2023

Higher infliximab concentrations tied to better outcomes in paediatric CD

25 Mar 2023

Higher concentrations of infliximab postinduction results in favourable clinical outcomes in paediatric patients with Crohn’s disease (CD) both in the short and long term, reports a study.

Higher infliximab concentrations tied to better outcomes in paediatric CD

25 Mar 2023

Sleep loss ups hunger-promoting hormones in adults

25 Mar 2023

A recent study has shown that acute sleep deprivation leads to a decrease in blood concentrations of satiety-hormone leptin and to an increase in ghrelin and adiponectin, which induce hunger.

Sleep loss ups hunger-promoting hormones in adults

25 Mar 2023

Perfluorohexyloctane eye drops for dry eye disease impresses in phase III trial

25 Mar 2023

The novel NOV03 ophthalmic drop consisting of perfluorohexyloctane appears to help reduce both signs and symptoms of dry eye disease (DED) associated with meibomian gland dysfunction (MGD), as shown in the results of the phase III MOJAVE study.

Perfluorohexyloctane eye drops for dry eye disease impresses in phase III trial

25 Mar 2023

$Add-on vistusertib misses mark in platinum-resistant, refractory ovarian high-grade serous carcinoma$

Add-on vistusertib misses mark in platinum-resistant, refractory ovarian high-grade serous carcinoma

25 Mar 2023

Adding vistusertib to weekly paclitaxel does not appear to help improve clinical outcomes in patients with platinum-resistant or refractory ovarian high-grade serous carcinoma (PR-HGSC), according to the results of a phase II study.

Add-on vistusertib misses mark in platinum-resistant, refractory ovarian high-grade serous carcinoma

25 Mar 2023

Atorvastatin cardioprotective in lymphoma patients receiving anthracycline?

25 Mar 2023 by

Among patients with lymphoma receiving anthracycline-based chemotherapy, those who received atorvastatin for 12 months were significantly less likely to experience a cardiac dysfunction than those on placebo, according to the STOP-CA* trial presented at ACC.23/WCC.

Atorvastatin cardioprotective in lymphoma patients receiving anthracycline?

25 Mar 2023

Less salt may be fatally counterproductive for people with heart failure

24 Mar 2023 by

Too little salt is not necessarily better for individuals with heart failure, with the results of a recent meta-analysis suggesting that sodium restriction in this population increases the risk of death.

Less salt may be fatally counterproductive for people with heart failure

24 Mar 2023

BMI drives causal relationship of sleep apnoea, snoring with T2D

24 Mar 2023

Body mass index (BMI) appears to be the main mediator of the association of sleep apnoea and snoring with type 2 diabetes (T2D), suggests a study.

BMI drives causal relationship of sleep apnoea, snoring with T2D

24 Mar 2023

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Dual inhibition of EGFR, VEGF improves progression-free survival in NSCLC

Dual inhibition of EGFR, VEGF improves progression-free survival in NSCLC

Maternal Crohn’s disease ups risk of infection in offspring

Maternal Crohn’s disease ups risk of infection in offspring

Add-on pembrolizumab helps improve outcomes of relapsed, refractory Hodgkin lymphoma

Add-on pembrolizumab helps improve outcomes of relapsed, refractory Hodgkin lymphoma

Higher infliximab concentrations tied to better outcomes in paediatric CD

Higher infliximab concentrations tied to better outcomes in paediatric CD

Sleep loss ups hunger-promoting hormones in adults

Sleep loss ups hunger-promoting hormones in adults

Perfluorohexyloctane eye drops for dry eye disease impresses in phase III trial

Perfluorohexyloctane eye drops for dry eye disease impresses in phase III trial

Add-on vistusertib misses mark in platinum-resistant, refractory ovarian high-grade serous carcinoma

Add-on vistusertib misses mark in platinum-resistant, refractory ovarian high-grade serous carcinoma

Atorvastatin cardioprotective in lymphoma patients receiving anthracycline?

Atorvastatin cardioprotective in lymphoma patients receiving anthracycline?

Less salt may be fatally counterproductive for people with heart failure

Less salt may be fatally counterproductive for people with heart failure

BMI drives causal relationship of sleep apnoea, snoring with T2D

BMI drives causal relationship of sleep apnoea, snoring with T2D