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GLP-1 RAs reduce depression, substance use in young patients with obesity, MASLD

17 Jun 2025 by

In paediatric patients with obesity and metabolic dysfunction-associated steatotic liver disease (MASLD), treatment with GLP-1 receptor agonists (RAs) results in a decrease in depression and substance use, as shown in a study presented at ESPGHAN 2025.

GLP-1 RAs reduce depression, substance use in young patients with obesity, MASLD

17 Jun 2025

Final VEDOKIDS data: Remission with maintenance vedolizumab durable in UC, less so in CD

14 Jun 2025 by

Maintenance treatment with vedolizumab proved safe and effective in paediatric inflammatory bowel disease (IBD), with long-term remission achieved more frequently in children with ulcerative colitis (UC) than in those with Crohn’s disease (CD), according to the final 3-year data from the VEDOKIDS study.

Final VEDOKIDS data: Remission with maintenance vedolizumab durable in UC, less so in CD

14 Jun 2025

IBD tied to increased risk of rheumatoid arthritis

13 Jun 2025

Patients with inflammatory bowel disease (IBD) appear to be at heightened risk of rheumatoid arthritis (RA), as reported in a study.

IBD tied to increased risk of rheumatoid arthritis

13 Jun 2025

Functional abdominal pain in kids: Drotaverine, peppermint oil similar in head-to-head trial

13 Jun 2025 by

Both drotaverine and peppermint oil are safe and help alleviate abdominal pain in children whose pain cannot be attributed to a specific medical condition, with neither treatment demonstrating clear superiority over the other, according to the results of a single-blind, randomized controlled trial.

Functional abdominal pain in kids: Drotaverine, peppermint oil similar in head-to-head trial

13 Jun 2025

Timely rectal cancer treatment extends survival outcomes

12 Jun 2025

The timing of rectal cancer treatment is crucial in improving patient survival, according to a study.

Timely rectal cancer treatment extends survival outcomes

12 Jun 2025

GCSF plus prednisolone extends survival in severe alcohol-associated hepatitis

11 Jun 2025

The addition of granulocyte colony-stimulating factor (GCSF) to prednisolone results in improved steroid responsiveness and prolonged survival with fewer infections and new-onset complications among patients with severe alcohol-associated hepatitis (SAH), a study has shown.

GCSF plus prednisolone extends survival in severe alcohol-associated hepatitis

11 Jun 2025

Long-term rectal cancer outcomes better with laparoscopic vs robotic surgery

10 Jun 2025 by

Three-year data from the REAL study has shown that robot-assisted resection of middle or low rectal cancer is associated with lower locoregional recurrence and disease-free survival compared with the conventional laparoscopic approach.

Long-term rectal cancer outcomes better with laparoscopic vs robotic surgery

10 Jun 2025

V-ERAT trumps antibiotics for uncomplicated acute appendicitis

10 Jun 2025

Patients with uncomplicated acute appendicitis may opt for visual endoscopic retrograde appendicitis therapy (V-ERAT) as a safe and effective alternative to antibiotic treatment to reduce the risk of recurrence, according to a study.

V-ERAT trumps antibiotics for uncomplicated acute appendicitis

10 Jun 2025

Are statins protective against HCC?

10 Jun 2025 by

In a study presented at EASL 2025, the use of statins appears to be associated with a reduced risk of hepatocellular carcinoma (HCC) and slower progression of liver fibrosis in individuals with chronic liver disease (CLD).

Are statins protective against HCC?

10 Jun 2025

Efruxifermin misses mark in MASH-related compensated cirrhosis

10 Jun 2025

Treatment with the bivalent fibroblast growth factor 21 (FGF21) analogue efruxifermin falls short of improving fibrosis in patients with compensated cirrhosis caused by metabolic dysfunction–associated steatohepatitis (MASH), according to a phase 2b study.

Efruxifermin misses mark in MASH-related compensated cirrhosis

10 Jun 2025

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GLP-1 RAs reduce depression, substance use in young patients with obesity, MASLD

GLP-1 RAs reduce depression, substance use in young patients with obesity, MASLD

Final VEDOKIDS data: Remission with maintenance vedolizumab durable in UC, less so in CD

Final VEDOKIDS data: Remission with maintenance vedolizumab durable in UC, less so in CD

IBD tied to increased risk of rheumatoid arthritis

IBD tied to increased risk of rheumatoid arthritis

Functional abdominal pain in kids: Drotaverine, peppermint oil similar in head-to-head trial

Functional abdominal pain in kids: Drotaverine, peppermint oil similar in head-to-head trial

Timely rectal cancer treatment extends survival outcomes

Timely rectal cancer treatment extends survival outcomes

GCSF plus prednisolone extends survival in severe alcohol-associated hepatitis

GCSF plus prednisolone extends survival in severe alcohol-associated hepatitis

Long-term rectal cancer outcomes better with laparoscopic vs robotic surgery

Long-term rectal cancer outcomes better with laparoscopic vs robotic surgery

V-ERAT trumps antibiotics for uncomplicated acute appendicitis

V-ERAT trumps antibiotics for uncomplicated acute appendicitis

Are statins protective against HCC?

Are statins protective against HCC?

Efruxifermin misses mark in MASH-related compensated cirrhosis

Efruxifermin misses mark in MASH-related compensated cirrhosis