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Mifepristone reduces HbA1c in adults with T2D, hypercortisolism

Treatment with mifepristone significantly reduced HbA_1c levels in patients with difficult-to-control type 2 diabetes (T2D) and hypercortisolism compared with placebo, according to the final results of the CATALYST trial presented at ADA 2025.

Mifepristone reduces HbA1c in adults with T2D, hypercortisolism

6 hours ago

Dual-Index Aspherical Lenslets deliver on myopia control in Singaporean kids

18 hours ago by

Wearing spectacle lenses with Dual-Index Aspherical Lenslets (DIAL) appears to be more efficacious at slowing myopia progression in children when compared with single-vision spectacle lenses (SVLs), as shown in a study from Singapore.

Dual-Index Aspherical Lenslets deliver on myopia control in Singaporean kids

18 hours ago

Social media posts show difficulties faced by sarcoma patients

19 hours ago

An analysis of social media posts reveals the interconnected challenges that patients with sarcoma have to go through, including treatment decisions, financial concerns, and work impact.

Social media posts show difficulties faced by sarcoma patients

19 hours ago

Subcutaneous on par with IV pembrolizumab for NSCLC

20 hours ago by

Pembrolizumab administered subcutaneously (SC) is noninferior to the intravenous (IV) strategy in terms of overall exposure and trough concentrations, with similar efficacy and consistent safety profiles in patients with treatment-naive metastatic nonsmall cell lung cancer (NSCLC), reports a study.

Subcutaneous on par with IV pembrolizumab for NSCLC

20 hours ago

Coeliac disease risk increased among patient kin

21 hours ago

First-degree relatives (FDRs) of patients with coeliac disease (CD) are at an elevated risk of developing CD, suggests a study.

Coeliac disease risk increased among patient kin

21 hours ago

Psychosis in cannabis users: Dopamine system may be the link

a day ago by

Patients with cannabis use disorder (SUD) have increased dopamine functioning in the brain pathway associated with psychosis, a longitudinal cohort study has shown.

Psychosis in cannabis users: Dopamine system may be the link

a day ago

Bevacizumab plus erlotinib shows promise in hereditary, sporadic papillary kidney cancer

a day ago

Combination treatment with bevacizumab plus erlotinib appears to work against hereditary leiomyomatosis and renal-cell cancer (HLRCC)-associated or sporadic papillary renal-cell carcinoma, according to an open-label phase II study.

Bevacizumab plus erlotinib shows promise in hereditary, sporadic papillary kidney cancer

a day ago

Esketamine monotherapy shows robust, rapid efficacy as treatment for TRD

a day ago by

Intranasal esketamine, administered at two fixed doses as monotherapy for treatment-resistant depression (TRD), has demonstrated robust and rapid efficacy in a phase IV double-blind, placebo-controlled randomized trial.

Esketamine monotherapy shows robust, rapid efficacy as treatment for TRD

a day ago

Hepatic steatosis linked to lower mortality in CLD patients

a day ago

The presence of substantial hepatic steatosis estimated by controlled attenuated parameter (CAP) score among patients who underwent vibration-controlled transient elastography (VCTE) appears to reduce the risk of all-cause mortality and decompensation, particularly in those with metabolic dysfunction-associated steatotic liver disease (MASLD), reports a study.

Hepatic steatosis linked to lower mortality in CLD patients

a day ago

Oral frailty tied to worse physical, mental health in older adults

a day ago by

Oral frailty can lead to negative outcomes in older adults, including poorer physical health and reduced cognition, according to a study. Early identification can help prevent these harmful consequences.

Oral frailty tied to worse physical, mental health in older adults

a day ago

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Mifepristone reduces HbA1c in adults with T2D, hypercortisolism

Mifepristone reduces HbA1c in adults with T2D, hypercortisolism

Dual-Index Aspherical Lenslets deliver on myopia control in Singaporean kids

Dual-Index Aspherical Lenslets deliver on myopia control in Singaporean kids

Social media posts show difficulties faced by sarcoma patients

Social media posts show difficulties faced by sarcoma patients

Subcutaneous on par with IV pembrolizumab for NSCLC

Subcutaneous on par with IV pembrolizumab for NSCLC

Coeliac disease risk increased among patient kin

Coeliac disease risk increased among patient kin

Psychosis in cannabis users: Dopamine system may be the link

Psychosis in cannabis users: Dopamine system may be the link

Bevacizumab plus erlotinib shows promise in hereditary, sporadic papillary kidney cancer

Bevacizumab plus erlotinib shows promise in hereditary, sporadic papillary kidney cancer

Esketamine monotherapy shows robust, rapid efficacy as treatment for TRD

Esketamine monotherapy shows robust, rapid efficacy as treatment for TRD

Hepatic steatosis linked to lower mortality in CLD patients

Hepatic steatosis linked to lower mortality in CLD patients

Oral frailty tied to worse physical, mental health in older adults

Oral frailty tied to worse physical, mental health in older adults