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Esketamine combined with SSRI or SNRI leads to different outcomes in treatment-resistant depression
Esketamine combined with a serotonin-norepinephrine reuptake inhibitor (SNRI) reduces rates of mortality, hospitalizations, and depressive relapses, while esketamine combined with a selective serotonin reuptake inhibitor (SSRI) decreases the incidence of suicidal attempts, a real-world comparative effectiveness study on treatment-resistant depression (TRD) has shown.
Esketamine combined with SSRI or SNRI leads to different outcomes in treatment-resistant depression
30 Apr 2025
Single-dose baloxavir reduces household transmission of influenza
A single dose of baloxavir given to an index patient (IP) reduces the odds of influenza transmission to untreated household contacts (HHCs) by 32 percent vs placebo, according to the results of the phase IIIb CENTERSTONE trial.
Single-dose baloxavir reduces household transmission of influenza
30 Apr 2025
Oral microbiota may identify autism in kids with >80 percent accuracy
Eleven oral bacterial species may serve as biomarkers for early detection of autism through simple oral sampling, with an accuracy of 81 percent, according to a cross-disciplinary research team from the Faculty of Dentistry and the Department of Psychology of the University of Hong Kong (HKU).
Oral microbiota may identify autism in kids with >80 percent accuracy
29 Apr 2025
Proteomic analysis identifies DKD progression markers in YT2D
A comprehensive analysis of circulating proteins identifies known and novel proteins associated with the progression of diabetic kidney disease (DKD) in Asians with younger-onset type 2 diabetes (YT2D; T2D onset age <40 years).
