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HKU programme offers free comprehensive genomic profiling tests to NSCLC patients
The University of Hong Kong (HKU) has launched a precision oncology programme in partnership with public and private stakeholders to provide free comprehensive genomic profiling tests to 1,800 eligible patients with stage IV non-small-cell lung cancer (NSCLC) in Hong Kong. Initial data from the programme revealed less common mutations amenable to treatment with targeted therapies in a sizeable proportion of patients.
HKU programme offers free comprehensive genomic profiling tests to NSCLC patients
14 Nov 2022
Dolutegravir: A better choice for HIV viral suppression in pregnancy?
Among pregnant individuals on antiretroviral therapy (ART) for HIV-1 infection, those on dolutegravir had the greatest viral suppression rates at delivery, a recent US-based observational study showed. However, birth outcomes generally did not differ between dolutegravir recipients and those on various other ART regimens.
Dolutegravir: A better choice for HIV viral suppression in pregnancy?
13 Nov 2022
Polygenic risk scores predict response to ECT for major depressive disorder
A polygenic liability for major depressive disorder and bipolar disorder contributes to improvements following electroconvulsive therapy (ECT), reports a study. This provides evidence of a genetic factor for clinical response to ECT.
Polygenic risk scores predict response to ECT for major depressive disorder
13 Nov 2022
Once-weekly semaglutide safe, effective in type 2 diabetes patients
Initiating a once-weekly treatment regimen of semaglutide helps control glycated haemoglobin (HbA1c) levels and body weight in patients with type 2 diabetes, without introducing new safety concerns, a Japan study has found.
Once-weekly semaglutide safe, effective in type 2 diabetes patients
13 Nov 2022
Genetic, environmental factors drive metabolic disorder-related depression
The risk of depression is higher in individuals with endocrine-metabolic disorders, which can be explained by genetic and environmental influences, reveals a study.
Genetic, environmental factors drive metabolic disorder-related depression
12 Nov 2022
Cinnamic aldehyde, alcohol cause reactions in fragrance allergy
A prospective study has revealed that cinnamic aldehyde and cinnamic alcohol are the most common allergens that cause immediate and delayed reactions among patients with allergic contact dermatitis to fragrance. In addition, reactions to benzyl alcohol, sorbic acid, and coumarin are usually seen in immediate patch tests.