News & Updates

Ruxolitinib cream improves repigmentation in patients with vitiligo

09 Nov 2021 by

The application of ruxolitinib cream led to significant improvements in facial and total body repigmentation among adolescents and adults with vitiligo, according to two phase III studies presented at EADV 2021.

Ruxolitinib cream improves repigmentation in patients with vitiligo

09 Nov 2021

Omeprazole helps inhibit fatty acid synthase activity in triple-negative breast cancer

08 Nov 2021

Fatty acid synthase (FASN) is commonly expressed in operable triple-negative breast cancer (TNBC) and is associated with a poor prognosis, but omeprazole can hamper FASN activity, which may potentially boost the efficacy of neoadjuvant chemotherapy, according to the results of a phase II study.

Omeprazole helps inhibit fatty acid synthase activity in triple-negative breast cancer

08 Nov 2021

Quadruple therapy with empagliflozin/dapagliflozin affords long-term glycaemic control

08 Nov 2021 by

A four-drug combination that includes either empagliflozin or dapagliflozin helps keep glucose in check through 3 years for patients with type 2 diabetes (T2D), in addition to its positive effect on weight and tolerable safety profile, as shown in an open-label randomized controlled study.

Quadruple therapy with empagliflozin/dapagliflozin affords long-term glycaemic control

08 Nov 2021

Baseline circadian BP profile influences response to oral appliance therapy for OSA

08 Nov 2021

Circadian blood pressure (BP) profile at baseline has a significant impact on BP response to oral appliance therapy, primarily due to higher baseline BP in the nondipper subgroup, a study has shown. Thus, the therapy fails to convert obstructive sleep apnoea (OSA) patients to a more favourable circadian BP profile.

Baseline circadian BP profile influences response to oral appliance therapy for OSA

08 Nov 2021

Southeast Asia falls behind COVID-19 vaccination target: What must be done?

08 Nov 2021 by

Half of Southeast Asian countries are lagging in vaccinating people against COVID-19, with Myanmar, the Philippines, and Vietnam being the top three worst performers after having fully vaccinated only 8.3 percent, 19 percent, and 23 percent of their total population, respectively, as of 27 October 2021.

Southeast Asia falls behind COVID-19 vaccination target: What must be done?

08 Nov 2021

Phase III study CONFIRMs nivolumab potential for mesothelioma treatment

08 Nov 2021 by

The anti-PD-1 antibody nivolumab demonstrated potential as a treatment alternative for relapsed malignant mesothelioma that has progressed following first-line chemotherapy (CT), the phase III CONFIRM* trial has shown.

Phase III study CONFIRMs nivolumab potential for mesothelioma treatment

08 Nov 2021

Neuroadrenergic activation noted in OSA via MSNA, heart rate

08 Nov 2021

Obstructive sleep apnoea syndrome (OSAS) exhibits an evident sympathetic activation even when uncomplicated by other cardiometabolic diseases, as manifested by the muscle sympathetic nerve activity (MSNA) and heart rate (HR) behaviour, a study has shown.

Neuroadrenergic activation noted in OSA via MSNA, heart rate

08 Nov 2021

Paclitaxel HIPEC safe, effective in adenocarcinoma of oesophagogastric junction

08 Nov 2021

Hyperthermic intraperitoneal chemotherapy (HIPEC) improves postoperative cellular immune function in patients with adenocarcinoma of the oesophagogastric junction (AEG), a recent study has found.

Paclitaxel HIPEC safe, effective in adenocarcinoma of oesophagogastric junction

08 Nov 2021

Post-TAVI inflammatory response stronger with self-expandable vs balloon valves

08 Nov 2021 by

The use of self-expandable valves (SEV) for transcatheter aortic valve implantation (TAVI) triggers a more robust inflammatory response relative to balloon-expandable valves (BEV), according to a recent study.

Post-TAVI inflammatory response stronger with self-expandable vs balloon valves

08 Nov 2021

Antithrombotic drugs up bleeding risk after tooth extraction

08 Nov 2021

Antithrombotic drugs may lead to greater bleeding after tooth extraction, a recent study has found. Such an effect is modified by oral hygiene, age, and the number of extracted teeth.

Antithrombotic drugs up bleeding risk after tooth extraction

08 Nov 2021

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Ruxolitinib cream improves repigmentation in patients with vitiligo

Ruxolitinib cream improves repigmentation in patients with vitiligo

Omeprazole helps inhibit fatty acid synthase activity in triple-negative breast cancer

Omeprazole helps inhibit fatty acid synthase activity in triple-negative breast cancer

Quadruple therapy with empagliflozin/dapagliflozin affords long-term glycaemic control

Quadruple therapy with empagliflozin/dapagliflozin affords long-term glycaemic control

Baseline circadian BP profile influences response to oral appliance therapy for OSA

Baseline circadian BP profile influences response to oral appliance therapy for OSA

Southeast Asia falls behind COVID-19 vaccination target: What must be done?

Southeast Asia falls behind COVID-19 vaccination target: What must be done?

Phase III study CONFIRMs nivolumab potential for mesothelioma treatment

Phase III study CONFIRMs nivolumab potential for mesothelioma treatment

Neuroadrenergic activation noted in OSA via MSNA, heart rate

Neuroadrenergic activation noted in OSA via MSNA, heart rate

Paclitaxel HIPEC safe, effective in adenocarcinoma of oesophagogastric junction

Paclitaxel HIPEC safe, effective in adenocarcinoma of oesophagogastric junction

Post-TAVI inflammatory response stronger with self-expandable vs balloon valves

Post-TAVI inflammatory response stronger with self-expandable vs balloon valves

Antithrombotic drugs up bleeding risk after tooth extraction

Antithrombotic drugs up bleeding risk after tooth extraction