News & Updates

Novel tenofovir formulation noninferior to disoproxil fumarate in chronic hepatitis B

08 Nov 2021

In the treatment of patients with chronic hepatitis B (CHB), the novel tenofovir amibufenamide (TMF) is as good as tenofovir disoproxil fumarate (TDF) in terms of efficacy but with the advantage of better bone and renal safety, according to the results of a noninferiority trial.

Novel tenofovir formulation noninferior to disoproxil fumarate in chronic hepatitis B

08 Nov 2021

Endovascular device implants detrimental to patients with confirmed nickel allergy

07 Nov 2021

Patch-test confirmed nickel hypersensitivity appears to heighten the risk of adverse outcomes following implantation of a nickel-containing endovascular device, a study has found.

Endovascular device implants detrimental to patients with confirmed nickel allergy

07 Nov 2021

Original New Drug Application Approvals by US FDA (16-31 October 2021)

07 Nov 2021

New drug applications approved by US FDA as of 16-31 October 2021 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16-31 October 2021)

07 Nov 2021

Chronic respiratory symptoms in young adulthood tied to CVD, mortality risks in midlife

07 Nov 2021

Young adults with chronic respiratory symptoms are at high risk of cardiovascular disease (CVD) and all-cause mortality in midlife, with the risk increase independent of established cardiovascular risk factors, smoking and lung function, a study reports.

Chronic respiratory symptoms in young adulthood tied to CVD, mortality risks in midlife

07 Nov 2021

Enhanced, reduced vasodilation treatments carry opposite effects on central aortic BP in CKD

07 Nov 2021

Enhanced (EVT) and reduced vasodilation treatment (RVT) deliver contradictory impacts on central aortic blood pressure (cBP) in patients with chronic kidney disease (CKD), reports a study. Moreover, the difference between cBP and ambulatory BP is larger for EVT than RVT.

Enhanced, reduced vasodilation treatments carry opposite effects on central aortic BP in CKD

07 Nov 2021

Standard rituximab dose appears inadequate to maintain B cell depletion in AAV

07 Nov 2021

Rituximab maintenance dosing of 500 mg every 6 months may not be enough to maintain B cell depletion in the treatment of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), suggests a recent study.

Standard rituximab dose appears inadequate to maintain B cell depletion in AAV

07 Nov 2021

Rituximab induces good remission rates in pemphigus vulgaris

07 Nov 2021

A single cycle of rituximab treatment for pemphigus vulgaris achieves >30 percent complete remission rate after 1 year, which improves with longer follow-up and additional cycles, a new study has found.

Rituximab induces good remission rates in pemphigus vulgaris

07 Nov 2021

Dyslipidaemia during pregnancy ups SGA risk

07 Nov 2021

Dyslipidaemia and elevated biosynthesis of cholesterol, even during the first trimester of pregnancy, increase the risk of small for gestational age (SGA) neonates, a recent study has found.

Dyslipidaemia during pregnancy ups SGA risk

07 Nov 2021

Early, more frequent egg intake may prevent egg allergy in childhood

06 Nov 2021 by

Late introduction of eggs, along with less frequent egg consumption, may place a child at increased risk of egg allergy during childhood, suggests a study presented at ACAAI 2021.

Early, more frequent egg intake may prevent egg allergy in childhood

06 Nov 2021

Retinal fluid volume variations during anti-VEGF maintenance therapy tied to worse VA

06 Nov 2021

Among patients with neovascular age-related macular degeneration (nAMD), fluctuations in retinal fluid volume during the maintenance phase antivascular endothelial growth factor (anti-VEGF) therapy may lead to long-term deterioration in visual acuity (VA), a recent study has found.

Retinal fluid volume variations during anti-VEGF maintenance therapy tied to worse VA

06 Nov 2021

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Novel tenofovir formulation noninferior to disoproxil fumarate in chronic hepatitis B

Novel tenofovir formulation noninferior to disoproxil fumarate in chronic hepatitis B

Endovascular device implants detrimental to patients with confirmed nickel allergy

Endovascular device implants detrimental to patients with confirmed nickel allergy

Original New Drug Application Approvals by US FDA (16-31 October 2021)

Original New Drug Application Approvals by US FDA (16-31 October 2021)

Chronic respiratory symptoms in young adulthood tied to CVD, mortality risks in midlife

Chronic respiratory symptoms in young adulthood tied to CVD, mortality risks in midlife

Enhanced, reduced vasodilation treatments carry opposite effects on central aortic BP in CKD

Enhanced, reduced vasodilation treatments carry opposite effects on central aortic BP in CKD

Standard rituximab dose appears inadequate to maintain B cell depletion in AAV

Standard rituximab dose appears inadequate to maintain B cell depletion in AAV

Rituximab induces good remission rates in pemphigus vulgaris

Rituximab induces good remission rates in pemphigus vulgaris

Dyslipidaemia during pregnancy ups SGA risk

Dyslipidaemia during pregnancy ups SGA risk

Early, more frequent egg intake may prevent egg allergy in childhood

Early, more frequent egg intake may prevent egg allergy in childhood

Retinal fluid volume variations during anti-VEGF maintenance therapy tied to worse VA

Retinal fluid volume variations during anti-VEGF maintenance therapy tied to worse VA