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Handgrip strength may help lower mortality risk in older adults with severe obesity

Handgrip strength is predictive of all-cause mortality risk in older adults with severe obesity, and this association points to some useful thresholds for reducing the risk of death, suggest the results of a multi-country cohort study.

Handgrip strength may help lower mortality risk in older adults with severe obesity

22 hours ago

GLP-1 RA use in T2DM may protect against peptic ulcer disease

a day ago

Patients with type 2 diabetes mellitus (T2DM) who use glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have lower odds of peptic ulcer disease when compared with insulin users, as shown in a retrospective study.

GLP-1 RA use in T2DM may protect against peptic ulcer disease

a day ago

Parathyroidectomy lowers risk of diabetes in patients with primary hyperparathyroidism

02 Sep 2025

For patients with primary hyperparathyroidism, parathyroidectomy may help prevent the development of diabetes, as reported in a study.

Parathyroidectomy lowers risk of diabetes in patients with primary hyperparathyroidism

02 Sep 2025

Metformin plus low-to-moderate FODMAP diet improves glycaemic control, BMI and gut microbiota in prediabetes

02 Sep 2025 by

A study by the Chinese University of Hong Kong (CUHK) in collaboration with Monash University, Australia, found that combining metformin therapy with a diet containing fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAPs) in individuals with prediabetes resulted in improved glycaemic control and gut microbiome, among other benefits, with greater effects seen with moderate-FODMAP (M-M) compared with low-FODMAP (L-M) regimens.

Metformin plus low-to-moderate FODMAP diet improves glycaemic control, BMI and gut microbiota in prediabetes

02 Sep 2025

Uveitis risk reduced with GLP-1RAs

01 Sep 2025

Users of glucagon-like peptide-1 receptor agonists (GLP-1RAs) are at lower risk of uveitis compared with nonusers, according to a retrospective study.

Uveitis risk reduced with GLP-1RAs

01 Sep 2025

Semaglutide 2.4 mg gets US FDA approval for MASH

01 Sep 2025 by

Subcutaneous (SC) semaglutide 2.4 mg QW is recently granted accelerated approval by the US FDA for treatment of metabolic dysfunction–associated steatohepatitis (MASH) in adults with moderate-to-advanced fibrosis.

Semaglutide 2.4 mg gets US FDA approval for MASH

01 Sep 2025

SGLT2 inhibitors confer cardiovascular, renal benefits in stage 4 CKM syndrome

31 Aug 2025 by

In the treatment of patients with stage 4 cardiovascular–kidney–metabolic (CKM) syndrome, sodium–glucose cotransporter 2 (SGLT2) inhibitors appear to exert cardio- and renoprotective effects, as shown in a retrospective study.

SGLT2 inhibitors confer cardiovascular, renal benefits in stage 4 CKM syndrome

31 Aug 2025

Familial hypercholesterolemia a risk factor for cerebral small vessel disease

30 Aug 2025

Individuals with familial hypercholesterolemia (FH) appear to be at increased risk of lacunes and cerebral microbleeds, as reported in a study from Japan.

Familial hypercholesterolemia a risk factor for cerebral small vessel disease

30 Aug 2025

SGLT2 inhibitors lower stroke, mortality risks in AF patients with T2DM

29 Aug 2025

Treatment with SGLT2 inhibitors appears to reduce the risks of stroke, dementia, long-standing persistent atrial fibrillation (AF), heart failure, and mortality in patients with both AF and type 2 diabetes mellitus (T2DM), suggests a recent study.

SGLT2 inhibitors lower stroke, mortality risks in AF patients with T2DM

29 Aug 2025

7,000 steps a day may be enough

29 Aug 2025 by

Walking 7,000 steps a day can offer the same health benefits as walking 10,000 steps a day, according to a comprehensive review and meta-analysis. Experts said it could be a more realistic target than the 10,000 steps, which is traditionally seen as the benchmark to reach.

7,000 steps a day may be enough

29 Aug 2025

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Handgrip strength may help lower mortality risk in older adults with severe obesity

Handgrip strength may help lower mortality risk in older adults with severe obesity

GLP-1 RA use in T2DM may protect against peptic ulcer disease

GLP-1 RA use in T2DM may protect against peptic ulcer disease

Parathyroidectomy lowers risk of diabetes in patients with primary hyperparathyroidism

Parathyroidectomy lowers risk of diabetes in patients with primary hyperparathyroidism

Metformin plus low-to-moderate FODMAP diet improves glycaemic control, BMI and gut microbiota in prediabetes

Metformin plus low-to-moderate FODMAP diet improves glycaemic control, BMI and gut microbiota in prediabetes

Uveitis risk reduced with GLP-1RAs

Uveitis risk reduced with GLP-1RAs

Semaglutide 2.4 mg gets US FDA approval for MASH

Semaglutide 2.4 mg gets US FDA approval for MASH

SGLT2 inhibitors confer cardiovascular, renal benefits in stage 4 CKM syndrome

SGLT2 inhibitors confer cardiovascular, renal benefits in stage 4 CKM syndrome

Familial hypercholesterolemia a risk factor for cerebral small vessel disease

Familial hypercholesterolemia a risk factor for cerebral small vessel disease

SGLT2 inhibitors lower stroke, mortality risks in AF patients with T2DM

SGLT2 inhibitors lower stroke, mortality risks in AF patients with T2DM

7,000 steps a day may be enough

7,000 steps a day may be enough