News & Updates

First-line treatment with ivonescimab significantly improves overall survival (OS) in patients with PD-L1-positive (PD-L1+) locally advanced or metastatic nonsmall cell lung cancer (NSCLC) compared with pembrolizumab, according to a prespecified interim analysis of the phase III HARMONi-2 trial presented at WCLC 2026.

There are two parts to managing any medical condition: the components of the therapeutic plan and the patient. Our job is to tailor the plan to best suit that individual patient’s needs.

Trigger Finger (TF), also known as stenosing tenosynovitis, is one of the most common causes of hand or digit pain seen at the Hand Clinic. Inflammatory changes are not seen histologically, but the tendon sheath (tendovagina) is thickened therefore more apt to be called tenovaginitis. It is basically a mechanical mismatch due to inflamed flexor tendons (flexor digitorum superficialis and profundus) and the thickened overlying retinacular pulley system (mostly theA1pulley) constricting them as they to go through the base of the digit. This restriction leads to friction, progressive tendon thickening, nodule formation, and the classic clinical presentation of painful digital catching, snapping, or locking inflexion.

Type 2 diabetes (T2D) patients receiving a glucagon-like peptide-1 receptor agonist (GLP-1 RA) and a sodium-glucose cotransporter-2 inhibitor (SGLT-2i) concomitantly appear to be at lower risk of dementia compared with those receiving a GLP-1 RA or SGLT-2i monotherapy, according to a study.

Lipid parameters tend to get worse during the early remission phase following curative surgery for Cushing’s syndrome (CS), reveals a study.

Intracranial abscesses in paediatric patients, although rare, need intensive multidisciplinary care, suggests a study, noting significant heterogeneity in current treatment strategies.

Many sonographers in Singapore have work-related musculoskeletal disorders despite good ergonomic awareness, according to a local study.