News &amp; Updates

Acute kidney injury in preemies tied to poor neurodevelopmental outcomes

Preterm infants with acute kidney injury (AKI) may have poor neurodevelopmental outcomes, according to a study.

Acute kidney injury in preemies tied to poor neurodevelopmental outcomes

Enfortumab vedotin plus pembrolizumab confers survival benefit in MIBC

19 Nov 2025 by

Adding perioperative enfortumab vedotin and pembrolizumab (EV + pembro) to surgery with radical cystectomy plus standard pelvic lymph node dissection (RC + PLND) significantly improves event-free survival (EFS) and overall survival (OS) in patients with muscle-invasive bladder cancer (MIBC) who are ineligible for cisplatin-based therapy, based on the first interim analysis of the phase III KEYNOTE-905 study presented at ESMO 2025.

Enfortumab vedotin plus pembrolizumab confers survival benefit in MIBC

Fixed-dose 4F-PCC safe, effective for FXal reversal in non-neurologic bleeds

A fixed-dose four-factor prothrombin complex concentrate (4F-PCC) demonstrates both safety and efficacy for factor Xa inhibitor (FXal) reversal in patients with non-neurologic haemorrhage, according to a recent study.

Fixed-dose 4F-PCC safe, effective for FXal reversal in non-neurologic bleeds

Updated CNS tumour epidemiology in Southeast Asia may guide future studies

18 Nov 2025 by

A study in Singapore has provided a comprehensive update of the epidemiology of brain and spinal tumours managed surgically, helping guide future research on central nervous system (CNS) tumours.

Updated CNS tumour epidemiology in Southeast Asia may guide future studies

Accumulated daily steps in longer bouts tied to fewer mortality, CVD events

Daily accumulated steps in longer bouts appear to result in lower mortality and cardiovascular disease (CVD) risks than steps accumulated in shorter bouts among suboptimally active adults, reveals a study.

Accumulated daily steps in longer bouts tied to fewer mortality, CVD events

Kidney stone history linked to poor survival outcomes in upper tract urothelial carcinoma

Among patients with upper tract urothelial carcinoma (UTUC) who underwent radical nephroureterectomy, those with a history of urinary tract stones appear to have poorer cancer-specific survival (CSS) and disease-free survival (DFS), according to a study.

Kidney stone history linked to poor survival outcomes in upper tract urothelial carcinoma

Rituximab works as relapse prevention in adult nephrotic syndrome

Treatment with rituximab helps prevent relapse in adult patients with frequently relapsing nephrotic syndrome (FRNS) or steroid-dependent nephrotic syndrome (SDNS), as shown in a study.

Rituximab works as relapse prevention in adult nephrotic syndrome

Closed-loop insulin system improves T1D management in pregnancy

17 Nov 2025 by

For pregnant women with type 1 diabetes (T1D), the use of a closed-loop insulin system helps increase time spent in target glucose range, according to the open-label CIRCUIT trial.

Closed-loop insulin system improves T1D management in pregnancy

Mediterranean diet better than TDA in reducing IBS symptoms

The Mediterranean diet (MD) appears to be more effective than traditional dietary advice (TDA) in the management of irritable bowel syndrome (IBS) symptoms, suggests a study.

Mediterranean diet better than TDA in reducing IBS symptoms