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Lenacapavir serves its PURPOSE in young individuals

11 Aug 2025 by

Twice-yearly subcutaneous (SC) lenacapavir demonstrates high efficacy, favourable safety, and consistent pharmacokinetics (PK) as pre-exposure prophylaxis (PrEP) for HIV-negative youth (aged 16–25 years) in an analysis of the phase III PURPOSE 1 (P1) and PURPOSE 2 (P2) trials.

Lenacapavir serves its PURPOSE in young individuals

11 Aug 2025

Vitamin D implicated in systemic lupus erythematosus

11 Aug 2025

Patients with systemic lupus erythematosus (SLE) with low levels of vitamin D tend to have a more severe form of the disease, according to a systematic review and meta-analysis.

Vitamin D implicated in systemic lupus erythematosus

11 Aug 2025

Older paternal age a risk factor for poor reproductive outcomes after ICSI

10 Aug 2025 by

Paternal age appears to independently factor in the success of intracytoplasmic sperm injection (ICSI), with sperm from men over 45 years of age being associated with increased risk of miscarriage and lower live birth rates, according to a retrospective study.

Older paternal age a risk factor for poor reproductive outcomes after ICSI

10 Aug 2025

Coexposure to bisphenols linked to metabolic diseases

10 Aug 2025

A recent study has observed the association of bisphenol A (BPA) and its substitutes with specific metabolic diseases (MDs).

Coexposure to bisphenols linked to metabolic diseases

10 Aug 2025

Pregabalin use for noncancer pain linked to increased risk of HF

10 Aug 2025

In the treatment of chronic noncancer pain, the use of pregabalin appears to be associated with a higher incidence of heart failure (HF) when compared with gabapentin, according to a retrospective cohort study.

Pregabalin use for noncancer pain linked to increased risk of HF

10 Aug 2025

Natalizumab, ocrelizumab equally effective in multiple sclerosis

09 Aug 2025 by

In patients with relapsing or progressing multiple sclerosis (MS), clinical outcomes are similar following treatment with natalizumab vs ocrelizumab, according to a retrospective study.

Natalizumab, ocrelizumab equally effective in multiple sclerosis

09 Aug 2025

Outcomes after sleeve gastrectomy differ across race, ethnicities

09 Aug 2025

Glycaemic outcomes following sleeve gastrectomy (SG) vary by race and ethnicity, with non-Hispanic Black (NHB) participants showing less favourable outcomes, reports a study.

Outcomes after sleeve gastrectomy differ across race, ethnicities

09 Aug 2025

Clozapine use tied to increased infection risk in schizophrenia

09 Aug 2025

Among patients receiving treatment for schizophrenia, infections appear to occur at a higher rate with clozapine vs olanzapine, as shown in a study from Hong Kong.

Clozapine use tied to increased infection risk in schizophrenia

09 Aug 2025

GLP-1RAs may provide migraine relief independent of weight loss

08 Aug 2025 by

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have the potential to reduce the frequency of migraines even in patients who do not lose weight—an effect that may be related to a reduction in intracranial pressure, according to a pilot prospective observational study.

GLP-1RAs may provide migraine relief independent of weight loss

08 Aug 2025

$Cataracts may raise risk of fractures$

Cataracts may raise risk of fractures

08 Aug 2025

Individuals with cataracts are more likely to experience fractures than those without the condition, suggests a study. However, people who have undergone cataract surgery appear to have a significantly lower fracture risk, offering a potential protective effect.

Cataracts may raise risk of fractures

08 Aug 2025

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Lenacapavir serves its PURPOSE in young individuals

Lenacapavir serves its PURPOSE in young individuals

Vitamin D implicated in systemic lupus erythematosus

Vitamin D implicated in systemic lupus erythematosus

Older paternal age a risk factor for poor reproductive outcomes after ICSI

Older paternal age a risk factor for poor reproductive outcomes after ICSI

Coexposure to bisphenols linked to metabolic diseases

Coexposure to bisphenols linked to metabolic diseases

Pregabalin use for noncancer pain linked to increased risk of HF

Pregabalin use for noncancer pain linked to increased risk of HF

Natalizumab, ocrelizumab equally effective in multiple sclerosis

Natalizumab, ocrelizumab equally effective in multiple sclerosis

Outcomes after sleeve gastrectomy differ across race, ethnicities

Outcomes after sleeve gastrectomy differ across race, ethnicities

Clozapine use tied to increased infection risk in schizophrenia

Clozapine use tied to increased infection risk in schizophrenia

GLP-1RAs may provide migraine relief independent of weight loss

GLP-1RAs may provide migraine relief independent of weight loss

Cataracts may raise risk of fractures

Cataracts may raise risk of fractures