News & Updates

A generalist-led care, the Integrated General Hospital (IGH) care model, demonstrates a numerically lower number of deaths and clinical outcomes comparable to a specialist-led care, the usual care model, as shown in a Singapore study. Patient care experiences with IGH are also positive.

The American College of Rheumatology/European Alliance of Associations for Rheumatology (ACR/EULAR) Total Improvement Score (TIS) may be used in research autoimmune inflammatory myopathies (AIM), according to a study.

Patients with chronic hepatitis B (CHB) infection who consume high levels of alcohol are at increased risk of hepatocellular carcinoma (HCC), as suggested in a retrospective study from China.

A report from Children’s Oncology Group (COG) AALL1731 study showed that paediatric patients with standard-risk (SR) B-cell acute lymphoblastic leukaemia (B-ALL) with undetectable minimal residual disease (MRD) at end of induction (EOI) by flow cytometry (FC) but not high-throughput sequencing (HTS) had inferior outcomes on chemotherapy alone, which were partially but not entirely mitigated by blinatumomab. In addition, outcomes of chemotherapy-only treatment among patients with MRD by HTS were not superior to those of patients with detectable MRD.

Among people living with HIV who are initiating antiretroviral therapy (ART), those with obesity potentially face a higher long-term risk of cardiovascular disease (CVD), cancer, or death, according to an observational study.

Some biomarkers of one-carbon metabolism are associated with toxicities induced by chemotherapy in patients with stage II‒III colorectal cancer (CRC), suggests a study.

Measurements of rituximab serum concentration are predictive of future drug concentrations associated with early B-cell repopulation in children with inflammatory diseases, suggests a study.

A hearing aid intervention does little to reduce the incidence of dementia-level impairment in older adults with coexisting hearing loss and mild cognitive impairment (MCI), as shown in the CHOICE trial.