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Insulin glargine plus lixisenatide improves outcomes in Chinese adults with T2D

17 Dec 2025 by

Treatment with iGlarLixi* resulted in better clinical outcomes than IDegAsp** in Chinese adults with type 2 diabetes (T2D), regardless of age or disease duration at baseline, according to a post hoc analysis of the phase III Soli-D study presented at ATTD-ASIA 2025.

Insulin glargine plus lixisenatide improves outcomes in Chinese adults with T2D

17 Dec 2025

Abnormalities in kidney, ureter, bladder tied to UTI recurrence, renal scarring in infants

16 Dec 2025 by

In infants who had a first urinary tract infection (UTI), the risks of recurrence and renal scarring appear to be high in the presence of kidney, ureter, and bladder abnormalities on ultrasound, according to a retrospective study from Singapore.

Abnormalities in kidney, ureter, bladder tied to UTI recurrence, renal scarring in infants

16 Dec 2025

Chemo plus targeted therapy extends survival in advanced BRAF-mutated CRC

16 Dec 2025 by

The combination of chemotherapy and anti-EGFR/BRAF therapy provides optimal survival benefits to patients with advanced BRAF-mutated colorectal cancer (CRC), according to a study.

Chemo plus targeted therapy extends survival in advanced BRAF-mutated CRC

16 Dec 2025

Laparoscopic nephrectomy ups risk for scrotal surgery in male kidney donors

16 Dec 2025

Undergoing laparoscopic nephrectomy may increase the risk for subsequent scrotal surgery in male living kidney donors, reports a study.

Laparoscopic nephrectomy ups risk for scrotal surgery in male kidney donors

16 Dec 2025

Add-on ON101 cost-effective for DFUs

16 Dec 2025 by

An economic analysis shows the cost-effectiveness of adding ON101 to general wound care (GWC) for the treatment of diabetic foot ulcers (DFUs) in individuals with type 2 diabetes (T2D) in Singapore, with robust results across subgroup and sensitivity analyses.

Add-on ON101 cost-effective for DFUs

16 Dec 2025

Tinengotinib shows promising activity against cholangiocarcinoma

16 Dec 2025

In patients with cholangiocarcinoma with FGFR2 fusions that progressed following FGFR inhibitor therapy, tinengotinib has demonstrated potential antitumour activity in a phase II study.

Tinengotinib shows promising activity against cholangiocarcinoma

16 Dec 2025

Oral PCSK9 inhibitor lowers LDL-C by up to 60 percent

16 Dec 2025 by

The oral PCSK9 inhibitor enlicitide lowers LDL-cholesterol (LDL-C) levels and other atherogenic lipids in high-risk patients with hypercholesterolaemia, as shown in the CORALreef Lipids study presented at AHA 2025.

Oral PCSK9 inhibitor lowers LDL-C by up to 60 percent

16 Dec 2025

Deaths from C. difficile higher in women, White patients

16 Dec 2025 by

Despite advances in infection control and antimicrobial stewardship, mortality from Clostridioides difficile (C. difficile) enterocolitis continues to disproportionately affect certain populations in the US, according to an analysis of the CDC WONDER database presented at IDWeek 2025.

Deaths from C. difficile higher in women, White patients

16 Dec 2025

HFrEF outcomes due to Chagas disease no better with sacubitril/valsartan vs enalapril

15 Dec 2025

In the treatment of patients with heart failure with reduced ejection fraction (HFrEF) secondary to Chagas disease, the use of sacubitril/valsartan does not appear to lead to improvements in clinical outcomes compared with enalapril, according to a study.

HFrEF outcomes due to Chagas disease no better with sacubitril/valsartan vs enalapril

15 Dec 2025

Laughing gas touted as rapid-acting antidepressant in meta-analysis

15 Dec 2025 by

Administration of nitrous oxide (N2O) appears to alleviate depressive symptoms as quickly as 2 h, according to a meta-analysis.

Laughing gas touted as rapid-acting antidepressant in meta-analysis

15 Dec 2025

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Insulin glargine plus lixisenatide improves outcomes in Chinese adults with T2D

Insulin glargine plus lixisenatide improves outcomes in Chinese adults with T2D

Abnormalities in kidney, ureter, bladder tied to UTI recurrence, renal scarring in infants

Abnormalities in kidney, ureter, bladder tied to UTI recurrence, renal scarring in infants

Chemo plus targeted therapy extends survival in advanced BRAF-mutated CRC

Chemo plus targeted therapy extends survival in advanced BRAF-mutated CRC

Laparoscopic nephrectomy ups risk for scrotal surgery in male kidney donors

Laparoscopic nephrectomy ups risk for scrotal surgery in male kidney donors

Add-on ON101 cost-effective for DFUs

Add-on ON101 cost-effective for DFUs

Tinengotinib shows promising activity against cholangiocarcinoma

Tinengotinib shows promising activity against cholangiocarcinoma

Oral PCSK9 inhibitor lowers LDL-C by up to 60 percent

Oral PCSK9 inhibitor lowers LDL-C by up to 60 percent

Deaths from C. difficile higher in women, White patients

Deaths from C. difficile higher in women, White patients

HFrEF outcomes due to Chagas disease no better with sacubitril/valsartan vs enalapril

HFrEF outcomes due to Chagas disease no better with sacubitril/valsartan vs enalapril

Laughing gas touted as rapid-acting antidepressant in meta-analysis

Laughing gas touted as rapid-acting antidepressant in meta-analysis