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Antiviral therapy prevents recurrence in CMV-AU

04 Jan 2026

A recent study has observed a very high recurrence rate for cytomegalovirus (CMV) anterior uveitis (AU), but this can be resolved by antiviral therapy.

Antiviral therapy prevents recurrence in CMV-AU

04 Jan 2026

Race, age linked to anti-VEGF initiation for nAMD

02 Jan 2026 by

One in five patients with neovascular age-related macular degeneration (nAMD) fail to start treatment within 1 year of presentation, reports a study. Factors associated with lower treatment initiation include Asian race, age <60 years, and low-vision status, among others.

Race, age linked to anti-VEGF initiation for nAMD

02 Jan 2026

Does antibiotic prophylaxis reduce SSI rates in children undergoing laparoscopic orchiopexy?

31 Dec 2025

Routine use of antibiotic prophylaxis does not appear to improve outcomes in children undergoing laparoscopic orchiopexy, reveals a recent study.

Does antibiotic prophylaxis reduce SSI rates in children undergoing laparoscopic orchiopexy?

31 Dec 2025

Obefazimod hits targets in identical trials on active UC

31 Dec 2025 by

Two phase III induction trials have demonstrated the efficacy and safety of obefazimod, an oral, first-in-class, small molecule, for the treatment of adults with moderate-to-severe ulcerative colitis (UC).

Obefazimod hits targets in identical trials on active UC

31 Dec 2025

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-November-2025

31 Dec 2025

New drug applications approved by US FDA as of 1-15 November 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-November-2025

31 Dec 2025

Lubiprostone use heightens risk of headache

30 Dec 2025

Treatment with lubiprostone is associated with an increased risk of headache in adults and children, according to a recent meta-analysis.

Lubiprostone use heightens risk of headache

30 Dec 2025

Mitapivat improves Hb levels in paediatric patients with PK deficiency

30 Dec 2025 by

Treatment with mitapivat increased haemoglobin (Hb) levels in children with pyruvate kinase (PK) deficiency who were not receiving regular blood transfusions, according to the ACTIVATE-Kids trial presented at ASH 2025.

Mitapivat improves Hb levels in paediatric patients with PK deficiency

30 Dec 2025

Subgroup analysis shows durable efficacy, safety of iptacopan for PNH treatment

29 Dec 2025 by

In a subgroup analysis of patients with paroxysmal nocturnal haemoglobinuria (PNH) with a history of aplastic anaemia and concomitant immunosuppressive therapy (AA + IST), long-term treatment with iptacopan yields clinically meaningful improvements in haemoglobin levels, transfusion needs, and haemolysis control, with safety outcomes comparable to those in individuals without AA.

Subgroup analysis shows durable efficacy, safety of iptacopan for PNH treatment

29 Dec 2025

What is the best intervention for fever-related discomfort in children?

28 Dec 2025 by

In children with fever-associated discomfort, pharmacological interventions appear safe and effective, while physical methods provide limited benefits, suggest the results of a systematic review.

What is the best intervention for fever-related discomfort in children?

28 Dec 2025

Pharmacogenomics combines pharmacology and genomics to better understand how genetic differences influence individual responses to medications.

26 Dec 2025 by

Genetic makeup may be the reason why some medicines function for some people but not others.

Pharmacogenomics combines pharmacology and genomics to better understand how genetic differences influence individual responses to medications.

26 Dec 2025

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Antiviral therapy prevents recurrence in CMV-AU

Antiviral therapy prevents recurrence in CMV-AU

Race, age linked to anti-VEGF initiation for nAMD

Race, age linked to anti-VEGF initiation for nAMD

Does antibiotic prophylaxis reduce SSI rates in children undergoing laparoscopic orchiopexy?

Does antibiotic prophylaxis reduce SSI rates in children undergoing laparoscopic orchiopexy?

Obefazimod hits targets in identical trials on active UC

Obefazimod hits targets in identical trials on active UC

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-November-2025

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-November-2025

Lubiprostone use heightens risk of headache

Lubiprostone use heightens risk of headache

Mitapivat improves Hb levels in paediatric patients with PK deficiency

Mitapivat improves Hb levels in paediatric patients with PK deficiency

Subgroup analysis shows durable efficacy, safety of iptacopan for PNH treatment

Subgroup analysis shows durable efficacy, safety of iptacopan for PNH treatment

What is the best intervention for fever-related discomfort in children?

What is the best intervention for fever-related discomfort in children?

Pharmacogenomics combines pharmacology and genomics to better understand how genetic differences influence individual responses to medications.

Pharmacogenomics combines pharmacology and genomics to better understand how genetic differences influence individual responses to medications.