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Lubiprostone use heightens risk of headache

30 Dec 2025

Treatment with lubiprostone is associated with an increased risk of headache in adults and children, according to a recent meta-analysis.

Lubiprostone use heightens risk of headache

30 Dec 2025

The establishment of SEACURE+ aims to enhance early detection and intervention of dementia in Asian populations.

23 Dec 2025 by

Malaysia is a member of the Southeast Asian Consortium on Neurocognition, Neuroimaging and Biomarker Research Plus (SEACURE+), the first consortium dedicated to tackling dementia in the region.

The establishment of SEACURE+ aims to enhance early detection and intervention of dementia in Asian populations.

23 Dec 2025

Impaired kidney function influences AD blood biomarkers but not dementia risk

17 Dec 2025 by

Among individuals without cognitive impairment, those with impaired kidney function exhibit increased levels of Alzheimer’s disease (AD) blood biomarkers, although they do not appear to be at increased risk of dementia compared with those who have preserved kidney function, according to new research.

Impaired kidney function influences AD blood biomarkers but not dementia risk

17 Dec 2025

EPVS burden a potential marker of CSVD, AD-related pathology

17 Dec 2025 by

A study from Singapore reports the potential of enlarged perivascular space (EPVS) burden as a marker of cerebral small vessel disease (CSVD) and Alzheimer’s disease (AD)-related blood-based biomarker (BBM) pathology.

EPVS burden a potential marker of CSVD, AD-related pathology

17 Dec 2025

Arterial stiffness linked to small-, large-fiber neuropathy

15 Dec 2025 by

A recent study has shown the association of greater arterial stiffening with both ocular (small) and peripheral (large) fiber neuropathies.

Arterial stiffness linked to small-, large-fiber neuropathy

15 Dec 2025

Outpatient use of nirmatrelvir/ritonavir cuts risk of severe COVID

13 Dec 2025

Outpatient use of nirmatrelvir/ritonavir lowers the risk of severe COVID-19-related outcomes, regardless of age or vaccination status, in a large, nationally representative cohort study in Taiwan, highlighting the importance of early antiviral treatment in ageing and unvaccinated populations.

Outpatient use of nirmatrelvir/ritonavir cuts risk of severe COVID

13 Dec 2025

Sleep apnoea may pose increased Parkinson’s disease risk

11 Dec 2025 by

People with obstructive sleep apnoea seem predisposed to later development of Parkinson’s disease, but this risk can be mitigated by early treatment with continuous positive airway pressure, as reported in a study.

Sleep apnoea may pose increased Parkinson’s disease risk

11 Dec 2025

Epilepsy risk elevated in children with congenital Zika syndrome

10 Dec 2025 by

New research suggests that in-utero exposure to Zika virus (ZIKV) alone does not increase the risk of epilepsy in early childhood, and the risk increase is limited to children who develop congenital Zika syndrome.

Epilepsy risk elevated in children with congenital Zika syndrome

10 Dec 2025

Plasma p-tau217 detects Alzheimer's disease in preclinical stage

09 Dec 2025 by

Plasma phosphorylated tau 217 (p-tau217) can identify pathological changes characteristic of Alzheimer’s disease (AD) in older adults without cognitive impairment, according to a meta-analysis.

Plasma p-tau217 detects Alzheimer's disease in preclinical stage

09 Dec 2025

Perimenopausal hormonal imbalances drive Alzheimer’s risk, plasma E2:P4 ratio a potential biomarker

09 Dec 2025 by

Researchers from the School of Life Sciences and the Gerald Choa Neuroscience Institute at the Chinese University of Hong Kong (CUHK) have found that estradiol (E2) to progesterone (P4) (E2:P4) imbalance during perimenopause likely increases the risk of Alzheimer’s disease (AD) and AD-related dementia in women via oestrogen-related receptor alpha (ERRα) dysfunction.

Perimenopausal hormonal imbalances drive Alzheimer’s risk, plasma E2:P4 ratio a potential biomarker

09 Dec 2025

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Lubiprostone use heightens risk of headache

Lubiprostone use heightens risk of headache

The establishment of SEACURE+ aims to enhance early detection and intervention of dementia in Asian populations.

The establishment of SEACURE+ aims to enhance early detection and intervention of dementia in Asian populations.

Impaired kidney function influences AD blood biomarkers but not dementia risk

Impaired kidney function influences AD blood biomarkers but not dementia risk

EPVS burden a potential marker of CSVD, AD-related pathology

EPVS burden a potential marker of CSVD, AD-related pathology

Arterial stiffness linked to small-, large-fiber neuropathy

Arterial stiffness linked to small-, large-fiber neuropathy

Outpatient use of nirmatrelvir/ritonavir cuts risk of severe COVID

Outpatient use of nirmatrelvir/ritonavir cuts risk of severe COVID

Sleep apnoea may pose increased Parkinson’s disease risk

Sleep apnoea may pose increased Parkinson’s disease risk

Epilepsy risk elevated in children with congenital Zika syndrome

Epilepsy risk elevated in children with congenital Zika syndrome

Plasma p-tau217 detects Alzheimer's disease in preclinical stage

Plasma p-tau217 detects Alzheimer's disease in preclinical stage

Perimenopausal hormonal imbalances drive Alzheimer’s risk, plasma E2:P4 ratio a potential biomarker

Perimenopausal hormonal imbalances drive Alzheimer’s risk, plasma E2:P4 ratio a potential biomarker