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Pembrolizumab plus CCRT improves survival in locally advanced cervical cancer

07 May 2025 by

Adding pembrolizumab to concurrent chemoradiotherapy (CCRT) improves progression-free survival (PFS) and overall survival (OS) in patients with high-risk, locally advanced cervical cancer (LACC) compared with CCRT alone, according to the second interim analysis of the phase III ENGOT-cx11/GOG-3047/KEYNOTE-A18 trial presented at SGO 2025.

07 May 2025

Cancer therapy takes a toll on women’s sexual health

06 May 2025 by

In women being treated for cervical cancer, chemotherapy and radiotherapy appear to have a substantial and lasting negative effect on sexual health, including satisfaction and desire, as shown in a descriptive cross-sectional study conducted in Brazil.

06 May 2025

Letrozole-abemaciclib plus metformin shows promise in endometrial cancer treatment

05 May 2025 by

Adding metformin to letrozole and abemaciclib does not cause serious safety concerns and may even encourage favourable responses among patients with oestrogen receptor (ER)-positive recurrent endometrial cancer (EC), according to a phase II study presented at SGO 2025.

05 May 2025

Biweekly Act-D vs multiday MTX: Which is better for GTN?

04 May 2025 by

Biweekly single-dose actinomycin-D (Act-D) is superior to 8-day methotrexate (MTX) regimen as first-line single-agent chemotherapy in patients with low-risk gestational trophoblastic neoplasia (GTN), as shown by a study presented at SGO 2025.

04 May 2025

Ibrexafungerp expands salvage antifungal treatment options as a pill

03 May 2025 by

For patients with fungal diseases that preclude receiving standard treatment or IV antifungals primarily due to refractoriness or resistance, ibrexafungerp can serve as an effective salvage treatment given orally, offering a positive risk-benefit ratio up to the final data cut-off in the FURI trial

03 May 2025

Self-perceived stress tied to higher stroke risk in young women

01 May 2025 by

A recent study found that self-perceived stress may increase the risk of early-onset cryptogenic ischaemic stroke (CIS) in young adults, particularly women.

01 May 2025

Progestin-only contraceptives may pose NAFLD risk among women with GDM history

25 Apr 2025 by

The use of progestin-only contraceptives may put women with a history of gestational diabetes mellitus (GDM) at risk of nonalcoholic fatty liver disease (NAFLD), as shown in a small prospective study.

25 Apr 2025

Add-on metformin of little benefit in advanced stage ovarian cancer

24 Apr 2025

Using metformin in addition to first-line platinum/taxane-based chemotherapy does not appear to produce survival gains in patients with newly diagnosed advanced stage ovarian cancer, according to a study.

24 Apr 2025

Is there a need for invasive urodynamics to manage OAB in women?

23 Apr 2025 by

Augmenting comprehensive clinical assessment (CCA) with invasive urodynamic investigations does not appear to benefit women with refractory overactive bladder (OAB) symptoms in the FUTURE* study presented at EAU25.

23 Apr 2025

Heparin use may prevent pre-eclampsia onset

22 Apr 2025

Thromboprophylaxis with low molecular weight heparin (LMWH) appears to protect against the onset of superimposed pre-eclampsia, independently from aspirin use, reports a recent study.