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Topicals are first in the new treatment order for knee osteoarthritis

18 Jun 2026 by

Knee osteoarthritis, increasingly common with ageing and obesity, often first presents to GPs, whose initial treatment decisions strongly shape outcomes and costs.

Topicals are first in the new treatment order for knee osteoarthritis

18 Jun 2026

Psilocybin demonstrates therapeutic potential in cocaine use disorder

18 Jun 2026

In the treatment of individuals with cocaine use disorder, the use of psilocybin may help improve abstinence rates and reduce the risk of cocaine lapse over time, as shown in a study.

Psilocybin demonstrates therapeutic potential in cocaine use disorder

18 Jun 2026

Add-on orforglipron improves outcomes in T2D patients on insulin glargine

17 Jun 2026 by

Daily treatment with oral orforglipron, when added to titrated insulin glargine, has been shown to be beneficial in individuals with inadequately controlled type 2 diabetes (T2D) in the phase 3 ACHIEVE-5 trial.

Add-on orforglipron improves outcomes in T2D patients on insulin glargine

17 Jun 2026

Tirzepatide superior to ICC in metformin-resistant T2D

17 Jun 2026

Treatment with tirzepatide yields robust reductions in HbA1c, weight, and waist circumference in patients with early type 2 diabetes (T2D) uncontrolled with metformin, reports a study.

Tirzepatide superior to ICC in metformin-resistant T2D

17 Jun 2026

COVID-19 vaccine improves survival outcomes in cancer patients on ICI therapy

17 Jun 2026 by

Vaccination against COVID-19 provides survival benefits to cancer patients receiving immune checkpoint inhibitors (ICIs), as shown in a recent study.

COVID-19 vaccine improves survival outcomes in cancer patients on ICI therapy

17 Jun 2026

Change in supine-to-standing SBP predicts mortality in females

17 Jun 2026

In healthy females, the change in supine-to-standing systolic blood pressure (SBP) is associated with mortality, regardless of traditional risk factors and antihypertensive medications, suggests a study.

Change in supine-to-standing SBP predicts mortality in females

17 Jun 2026

Sublingual cyclobenzaprine fares well in fibromyalgia

17 Jun 2026 by

Findings from the phase III RESILIENT study show that a sublingual formulation of cyclobenzaprine (CBP SL) may benefit individuals with fibromyalgia.

Sublingual cyclobenzaprine fares well in fibromyalgia

17 Jun 2026

Adjuvant nivolumab confers no DFS benefit in resected NSCLC

17 Jun 2026

In the treatment of patients with resected non–small cell lung cancer (NSCLC) without sensitizing EGFR and ALK alterations, adjuvant nivolumab does not appear to yield improvements in disease-free survival (DFS) when given after planned adjuvant chemotherapy and/or radiotherapy, according to a phase 3 study.

Adjuvant nivolumab confers no DFS benefit in resected NSCLC

17 Jun 2026

Which combo regimens are better tolerated for HTN?

17 Jun 2026 by

In a network meta-analysis of discontinuation of blood-pressure (BP)-lowering medications due to adverse effects (AEs), the best-tolerated treatment was a combination of an angiotensin receptor blocker (ARB) and a calcium channel blocker (CCB), with four of the top five best-tolerated regimens containing ARBs.

Which combo regimens are better tolerated for HTN?

17 Jun 2026

Antibiotic resistance genes found in newborn stool hours after birth

17 Jun 2026 by

Antibiotic resistance genes (ARGs)—DNA segments that enable bacterial survival in the presence of antibiotics— can be detected in newborns’ meconium shortly after birth, as shown in a study presented at ESCMID Global 2026.

Antibiotic resistance genes found in newborn stool hours after birth

17 Jun 2026

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Topicals are first in the new treatment order for knee osteoarthritis

Topicals are first in the new treatment order for knee osteoarthritis

Psilocybin demonstrates therapeutic potential in cocaine use disorder

Psilocybin demonstrates therapeutic potential in cocaine use disorder

Add-on orforglipron improves outcomes in T2D patients on insulin glargine

Add-on orforglipron improves outcomes in T2D patients on insulin glargine

Tirzepatide superior to ICC in metformin-resistant T2D

Tirzepatide superior to ICC in metformin-resistant T2D

COVID-19 vaccine improves survival outcomes in cancer patients on ICI therapy

COVID-19 vaccine improves survival outcomes in cancer patients on ICI therapy

Change in supine-to-standing SBP predicts mortality in females

Change in supine-to-standing SBP predicts mortality in females

Sublingual cyclobenzaprine fares well in fibromyalgia

Sublingual cyclobenzaprine fares well in fibromyalgia

Adjuvant nivolumab confers no DFS benefit in resected NSCLC

Adjuvant nivolumab confers no DFS benefit in resected NSCLC

Which combo regimens are better tolerated for HTN?

Which combo regimens are better tolerated for HTN?

Antibiotic resistance genes found in newborn stool hours after birth

Antibiotic resistance genes found in newborn stool hours after birth