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Esmethadone clears phase II trial as adjunctive treatment for major depressive disorder

08 Feb 2022

REL-1017 (esmethadone), a novel N-methyl-D-aspartate receptor channel blocker, demonstrates favourable safety, tolerability, and pharmacokinetic profiles and appears to have rapid and sustained antidepressant effects relative to placebo in major depressive disorder patients with inadequate responses to antidepressant treatments, according to a recent study.

Esmethadone clears phase II trial as adjunctive treatment for major depressive disorder

08 Feb 2022

Apatinib a new treatment alternative for thyroid cancer?

08 Feb 2022 by

In individuals with progressive locally advanced or metastatic radioactive iodine-refractory differentiated thyroid cancer (RAIR-DTC), the VEGFR-2* inhibitor apatinib demonstrated significant clinical benefits in terms of progression-free survival (PFS) and overall survival (OS), with a manageable safety profile, findings from the phase III REALITY trial suggest.

Apatinib a new treatment alternative for thyroid cancer?

08 Feb 2022

CGM with low-carb nutrition counselling boosts glycaemic control in T2DM

08 Feb 2022 by

The combination of continuous glucose monitoring (CGM) and low-carbohydrate nutrition counselling can help improve glycaemic control in patients with type 2 diabetes mellitus (T2DM), according to a recent study.

CGM with low-carb nutrition counselling boosts glycaemic control in T2DM

08 Feb 2022

Serological tests highly accurate for coeliac disease diagnosis

08 Feb 2022

Serological tests can reliably detect coeliac disease in children and adults, with the sensitivity of anti-tissue transglutaminase (tTG) being sufficient to rule out the disease while the high specificity of endomysial antibody (EMA) being useful for ruling in a diagnosis of the disease, according to the results of a systematic review and meta-analysis.

Serological tests highly accurate for coeliac disease diagnosis

08 Feb 2022

What puts pulmonary surgery patients at risk of prolonged air leak?

08 Feb 2022

In patients undergoing pulmonary surgery, smoking history, preoperative steroid use, and advanced malignancy increase the risk of prolonged air leak (PAL), reports a recent study.

What puts pulmonary surgery patients at risk of prolonged air leak?

08 Feb 2022

Novel XPO1 inhibitor shows antitumour activity in recurrent glioblastoma

08 Feb 2022

The oral selective inhibitor of exportin-1 (XPO1) selinexor has therapeutic potential in recurrent glioblastoma, yielding favourable responses and clinically relevant 6-month progression-free survival (PFS) rate with manageable side effects requiring dose reductions, according to the results of a phase II trial.

Novel XPO1 inhibitor shows antitumour activity in recurrent glioblastoma

08 Feb 2022

Original New Drug Application Approvals by US FDA (16 - 31 January 2022)

08 Feb 2022

New drug applications approved by US FDA as of 16-31 January 2022 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16 - 31 January 2022)

08 Feb 2022

First national cardiac electrophysiology summit unites a community

08 Feb 2022 by

The inaugural Malaysian Electrocardiography Summit 2021 (MECGS 2021) drew together experts and learners for the first national conference dedicated to cardiac electrophysiology (EP).

First national cardiac electrophysiology summit unites a community

08 Feb 2022

Regular follow-ups key to reducing eclampsia rates, maternal mortality

08 Feb 2022 by

Regular monitoring of expecting mothers can help reduce maternal death rates from eclampsia in the country, say experts.

Regular follow-ups key to reducing eclampsia rates, maternal mortality

08 Feb 2022

COVID-19 in 2021: Higher mortality rate among unvaccinated population

08 Feb 2022 by

COVID-19 deaths in Malaysia were consistently lower among vaccinated populations versus unvaccinated in the 7 months following the vaccine rollout, according to a recent study.

COVID-19 in 2021: Higher mortality rate among unvaccinated population

08 Feb 2022

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Esmethadone clears phase II trial as adjunctive treatment for major depressive disorder

Esmethadone clears phase II trial as adjunctive treatment for major depressive disorder

Apatinib a new treatment alternative for thyroid cancer?

Apatinib a new treatment alternative for thyroid cancer?

CGM with low-carb nutrition counselling boosts glycaemic control in T2DM

CGM with low-carb nutrition counselling boosts glycaemic control in T2DM

Serological tests highly accurate for coeliac disease diagnosis

Serological tests highly accurate for coeliac disease diagnosis

What puts pulmonary surgery patients at risk of prolonged air leak?

What puts pulmonary surgery patients at risk of prolonged air leak?

Novel XPO1 inhibitor shows antitumour activity in recurrent glioblastoma

Novel XPO1 inhibitor shows antitumour activity in recurrent glioblastoma

Original New Drug Application Approvals by US FDA (16 - 31 January 2022)

Original New Drug Application Approvals by US FDA (16 - 31 January 2022)

First national cardiac electrophysiology summit unites a community

First national cardiac electrophysiology summit unites a community

Regular follow-ups key to reducing eclampsia rates, maternal mortality

Regular follow-ups key to reducing eclampsia rates, maternal mortality

COVID-19 in 2021: Higher mortality rate among unvaccinated population

COVID-19 in 2021: Higher mortality rate among unvaccinated population