News & Updates

Unlocking the Secrets of Lipoprotein(a): A Global and Local Dive into Its Prevalence and Impact on Heart Health

25 Oct 2024

Lipoprotein(a) [Lp(a)] is a genetically determined variant of low density lipoprotein (LDL), consisting of apolipoprotein(a)[apo(a)] covalently linked by a disulphide bond to apolipoproteinB-100. The structure of Lp(a) varies considerably among individuals, primarily due to genetic polymorphisms in the LPA gene, which encodes the size of apo(a) and influences the concentration of Lp(a) particles in the plasma. Generally, individuals with fewer kringle IV type 2 repeats in the LPA gene tend to have smaller Lp(a) particles, which are associated with higher plasma Lp(a) levels.

Unlocking the Secrets of Lipoprotein(a): A Global and Local Dive into Its Prevalence and Impact on Heart Health

25 Oct 2024

IOP control still good 13 years after phacotrabeculectomy

25 Oct 2024 by

A retrospective case series at a tertiary hospital in Singapore has shown that the cumulative surgical success rate after phacotrabeculectomy remains high at 89.1 percent even 13 years post-surgery, with success defined as IOP ≤21 mm Hg

IOP control still good 13 years after phacotrabeculectomy

25 Oct 2024

Verinurad–allopurinol combo disappoints in HFpEF

24 Oct 2024

Combining verinurad with allopurinol does not appear to boost oxygen uptake or improve symptoms in heart failure with preserved ejection fraction (HFpEF), despite yielding significant reductions in serum uric acid (SUA) levels, according to a phase II study.

Verinurad–allopurinol combo disappoints in HFpEF

24 Oct 2024

High total primaquine dose provides superior protection against malaria recurrence in children

24 Oct 2024 by

A high total dose of primaquine outperforms a low dose at preventing the recurrence of Plasmodium vivax malaria in children, although it comes with more serious adverse events, according to the results of a meta-analysis.

High total primaquine dose provides superior protection against malaria recurrence in children

24 Oct 2024

Opioid use ups healthcare use, costs in adults with PsA, AS

24 Oct 2024

Patients with psoriatic arthritis (PsA) and ankylosing spondylitis (AS) who use opioids end up with higher healthcare utilization and costs compared with those who do not use opioids, reports a study.

Opioid use ups healthcare use, costs in adults with PsA, AS

24 Oct 2024

Semaglutide helps prevent HF events, CV death in diabetic patients with CKD

24 Oct 2024 by

Treatment with semaglutide can significantly lower the risk of time to first heart failure (HF) events or cardiovascular (CV) death in type 2 diabetes (T2D) patients with chronic kidney disease (CKD), a recent study has shown.

Semaglutide helps prevent HF events, CV death in diabetic patients with CKD

24 Oct 2024

At-term live births possible in pregnant women with vasculitis

24 Oct 2024

Women with vasculitis who get pregnant can deliver live births at term, although flares or hospitalization due to vasculitis may occur during pregnancy, according to a study.

At-term live births possible in pregnant women with vasculitis

24 Oct 2024

Mediterranean diet protective against COVID-19?

24 Oct 2024 by

A higher adherence to the Mediterranean diet (MedDiet) appears to reduce the odds of developing COVID-19, a systematic review suggests.

Mediterranean diet protective against COVID-19?

24 Oct 2024

VTE prophylaxis safe to administer in high-risk paediatric trauma patients

24 Oct 2024

Use of chemical venous thromboembolism (VTE) in paediatric trauma patients who meet the high-risk criteria is safe and does not appear to carry any risk of bleeding complications, according to a study.

VTE prophylaxis safe to administer in high-risk paediatric trauma patients

24 Oct 2024

Immediate brace weaning maintains similar outcomes to gradual weaning in adolescent idiopathic scoliosis

24 Oct 2024 by

A randomized clinical trial (RCT) conducted by researchers from the University of Hong Kong (HKU) demonstrated a very similar maintenance of outcomes and health-related quality of life (HRQoL) with immediate or gradual brace weaning in adolescent idiopathic scoliosis (AIS).

Immediate brace weaning maintains similar outcomes to gradual weaning in adolescent idiopathic scoliosis

24 Oct 2024

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Unlocking the Secrets of Lipoprotein(a): A Global and Local Dive into Its Prevalence and Impact on Heart Health

Unlocking the Secrets of Lipoprotein(a): A Global and Local Dive into Its Prevalence and Impact on Heart Health

IOP control still good 13 years after phacotrabeculectomy

IOP control still good 13 years after phacotrabeculectomy

Verinurad–allopurinol combo disappoints in HFpEF

Verinurad–allopurinol combo disappoints in HFpEF

High total primaquine dose provides superior protection against malaria recurrence in children

High total primaquine dose provides superior protection against malaria recurrence in children

Opioid use ups healthcare use, costs in adults with PsA, AS

Opioid use ups healthcare use, costs in adults with PsA, AS

Semaglutide helps prevent HF events, CV death in diabetic patients with CKD

Semaglutide helps prevent HF events, CV death in diabetic patients with CKD

At-term live births possible in pregnant women with vasculitis

At-term live births possible in pregnant women with vasculitis

Mediterranean diet protective against COVID-19?

Mediterranean diet protective against COVID-19?

VTE prophylaxis safe to administer in high-risk paediatric trauma patients

VTE prophylaxis safe to administer in high-risk paediatric trauma patients

Immediate brace weaning maintains similar outcomes to gradual weaning in adolescent idiopathic scoliosis

Immediate brace weaning maintains similar outcomes to gradual weaning in adolescent idiopathic scoliosis