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ARANOTE: Darolutamide plus ADT delays progression in mHSPC
The use of darolutamide (DARO) in addition to androgen deprivation therapy (ADT) is effective at improving radiological progression-free survival (rPFS) in patients with metastatic hormone-sensitive prostate cancer (mHSPC) compared with placebo plus ADT, irrespective of disease volume, according to the subanalysis of the phase III ARANOTE trial.
ARANOTE: Darolutamide plus ADT delays progression in mHSPC
28 Feb 2025
Low-dose aspirin halves recurrence risk in select CRC patients
In colorectal cancer (CRC) patients harbouring mutations in the PI3K pathway, adjuvant treatment with aspirin 160 mg daily reduced the recurrence rate by over 50 percent, according to the 3-year results from the ALASCCA trial.
Low-dose aspirin halves recurrence risk in select CRC patients
28 Feb 2025
Mevrometostat plus enzalutamide improves outcomes in mCRPC patients
Treatment with mevrometostat (MEV), an enhancer of zeste homolog 2 inhibitor, in combination with enzalutamide (ENZ) results in better survival outcomes and response than ENZ alone among patients with metastatic castration-resistant prostate cancer (mCRPC), reports a study presented at ASCO GU 2025. The combined therapy also demonstrates a favourable safety profile.
Mevrometostat plus enzalutamide improves outcomes in mCRPC patients
27 Feb 2025
Prenatal COVID-19 infection, vaccination: Early child developmental concerns allayed
Neither SARS-CoV-2 infection exposure nor COVID-19 vaccination during pregnancy poses a significant risk to early child development, as shown in a population-level study said to be the largest to date.