News & Updates

Stroke patients with NSAID allergy labels have poorer treatment outcomes

12 Feb 2025 by

Stroke patients with NSAID allergy labels have significantly higher mortality, peripheral vascular disease (PVD) and major adverse cardiovascular events (MACE) than those not labelled with NSAID allergies, and the rate of mislabelled NSAID allergy is high, a study by the University of Hong Kong (HKU) has found.

Stroke patients with NSAID allergy labels have poorer treatment outcomes

12 Feb 2025

Psilocybin shows promise for treatment-resistant depression

11 Feb 2025 by

The use of single-dose psilocybin offers potential safety and efficacy in patients with severe treatment-resistant depression (TRD), a study has shown.

Psilocybin shows promise for treatment-resistant depression

11 Feb 2025

Abelacimab outperforms rivaroxaban for AF patients at risk of stroke

11 Feb 2025

In the treatment of patients with atrial fibrillation (AF) and moderate-to-high risk of stroke, abelacimab appears more beneficial than rivaroxaban, having been associated with lower free factor XI levels and fewer bleeding events in the phase IIB AZALEA–TIMI 71 study.

Abelacimab outperforms rivaroxaban for AF patients at risk of stroke

11 Feb 2025

Old drugs, new tricks: Repositioning pitavastatin for glioblastoma treatment

11 Feb 2025 by

Nanostructured lipid carriers (NLCs) delivering pitavastatin demonstrated potential for glioblastoma (GB) treatment in a systematic benchtop study.

Old drugs, new tricks: Repositioning pitavastatin for glioblastoma treatment

11 Feb 2025

Certain HCC patients on atezolizumab–bevacizumab combo at risk of variceal bleeding

10 Feb 2025

Patients with hepatocellular carcinoma (HCC) who are receiving treatment with the combination of atezolizumab plus bevacizumab may be at risk of variceal bleeding, particularly those with a low platelet count, portal vein invasion, history of gastrointestinal bleeding, and varices needing treatment, as shown in a retrospective study.

Certain HCC patients on atezolizumab–bevacizumab combo at risk of variceal bleeding

10 Feb 2025

FMT of no benefit in systemic sclerosis patients with lower GI tract involvement

09 Feb 2025

Faecal microbiota transplantation (FMT) with standardized anaerobic cultivated human intestinal microbiome is safe but does not appear to be efficacious in patients with systemic sclerosis experiencing lower gastrointestinal (GI) tract symptoms, according to a phase II study.

FMT of no benefit in systemic sclerosis patients with lower GI tract involvement

09 Feb 2025

CheckMate 8HW makes case for doubling up on checkpoint inhibitors for mCRC

09 Feb 2025 by

Dual immunotherapy with checkpoint inhibitors nivolumab and ipilimumab works better to slow disease progression in patients with microsatellite instability-high or mismatch repair-deficient (MSI-H/dMMR) metastatic colorectal cancer (mCRC) when compared with single-agent nivolumab, as shown in the phase III CheckMate 8HW trial.

CheckMate 8HW makes case for doubling up on checkpoint inhibitors for mCRC

09 Feb 2025

Prenatal glucocorticoid exposure predisposes offspring to mental disorders

08 Feb 2025

Pregnant women who use glucocorticoids may put their offspring at risk of certain mental disorders, according to a large cohort study.

Prenatal glucocorticoid exposure predisposes offspring to mental disorders

08 Feb 2025

Selexipag demonstrates therapeutic potential in systemic sclerosis vasculopathy

08 Feb 2025

Preliminary data from an observational case–control study have shown that selexipag is safe and effective in the treatment of systemic sclerosis vasculopathy, particularly digital ulcers (DUs) and Raynaud phenomenon (RP).

Selexipag demonstrates therapeutic potential in systemic sclerosis vasculopathy

08 Feb 2025

Routine vaccines linked to higher risk of apnoea in hospitalized preterm infants

08 Feb 2025 by

Hospitalized preterm infants who received routine 2-month vaccinations were more likely to experience an apnoea episode within 48 hours than those who did not receive any vaccinations, according to a recent study.

Routine vaccines linked to higher risk of apnoea in hospitalized preterm infants

08 Feb 2025

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Stroke patients with NSAID allergy labels have poorer treatment outcomes

Stroke patients with NSAID allergy labels have poorer treatment outcomes

Psilocybin shows promise for treatment-resistant depression

Psilocybin shows promise for treatment-resistant depression

Abelacimab outperforms rivaroxaban for AF patients at risk of stroke

Abelacimab outperforms rivaroxaban for AF patients at risk of stroke

Old drugs, new tricks: Repositioning pitavastatin for glioblastoma treatment

Old drugs, new tricks: Repositioning pitavastatin for glioblastoma treatment

Certain HCC patients on atezolizumab–bevacizumab combo at risk of variceal bleeding

Certain HCC patients on atezolizumab–bevacizumab combo at risk of variceal bleeding

FMT of no benefit in systemic sclerosis patients with lower GI tract involvement

FMT of no benefit in systemic sclerosis patients with lower GI tract involvement

CheckMate 8HW makes case for doubling up on checkpoint inhibitors for mCRC

CheckMate 8HW makes case for doubling up on checkpoint inhibitors for mCRC

Prenatal glucocorticoid exposure predisposes offspring to mental disorders

Prenatal glucocorticoid exposure predisposes offspring to mental disorders

Selexipag demonstrates therapeutic potential in systemic sclerosis vasculopathy

Selexipag demonstrates therapeutic potential in systemic sclerosis vasculopathy

Routine vaccines linked to higher risk of apnoea in hospitalized preterm infants

Routine vaccines linked to higher risk of apnoea in hospitalized preterm infants