Alternating R-DA-EDOCH/R-DHAP induces deep remission in young Chinese patients with MCL
23 Mar 2025
byNatalia Reoutova
A phase III trial demonstrated a high minimal residual disease (MRD)-negativity rate with intensive continuous dose-adjusted rituximab plus etoposide, dexamethasone, doxorubicin, cyclophosphamide, and vincristine (R-DA-EDOCH) alternated with rituximab, dexamethasone, cytarabine, and cisplatin (R-DHAP), thereby offering an alternative induction therapy choice for young Chinese patients with mantle-cell lymphoma (MCL).