News &amp; Updates

First-line endocrine therapy (ET) plus palbociclib (palb/ET) performs better than mono-chemotherapy in improving time to treatment failure (TTF) and progression-free survival (PFS) in women with hormone receptor-positive (HR+), HER2-negative metastatic breast cancer (mBC), as shown by the results of the phase III PADMA trial.

Palbociclib plus ET prolongs survival in metastatic breast cancer

06 Jan 2025

T-DXd improves PFS in breast cancer with rapid progression

Treatment with trastuzumab deruxtecan (T-DXd) results in longer progression-free survival (PFS) in patients with hormone receptor–positive, HER2-low or HER2-ultralow metastatic breast cancer (mBC) compared with physician’s choice of chemotherapy, according to the results of the phase III DESTINY-Breast06 study presented at SABCS 2024. In addition, no new safety signals have been identified.

T-DXd improves PFS in breast cancer with rapid progression

06 Jan 2025

Gestational hypertension, preeclampsia, and eclampsia associated with future neurological disorders

Gestational hypertension, preeclampsia, and eclampsia were associated with an increased risk of new-onset migraine, headache, epilepsy, sleep disorder, or mental fatigue within months to years after giving birth, a Swedish study found.

Gestational hypertension, preeclampsia, and eclampsia associated with future neurological disorders

Vitamin D may protect against young-onset ischaemic stroke

Vitamin D may protect against young-onset ischaemic stroke through preventing atrial fibrillation (AF), a University of Hong Kong (HKU) study on Southern Chinese has found.

Vitamin D may protect against young-onset ischaemic stroke

Physical prehabilitation beneficial for prefrail/frail patients’ recovery after cardiac surgery

Vulnerable or frail patients who received physical prehabilitation, compared with those who received usual care, had clinically meaningful decrease in disability scores at 90 days after cardiac surgery, a Chinese University of Hong Kong (CUHK) study found.

Physical prehabilitation beneficial for prefrail/frail patients’ recovery after cardiac surgery

Real-world data confirm safety of dapagliflozin–metformin combo in T2DM

Using dapagliflozin and metformin together is well-tolerated and does not appear to cause additional safety concerns, according to a study involving Chinese patients with type 2 diabetes mellitus (T2DM) treated in routine clinical setting.

Real-world data confirm safety of dapagliflozin–metformin combo in T2DM

Machine learning-assisted spectroscopy enables subtype-specific breast cancer detection at early stage

05 Jan 2025 by

A screening method that integrates Raman spectroscopy (RS) with machine learning appears promising for the early detection and subtyping of breast cancer using blood plasma samples.

Machine learning-assisted spectroscopy enables subtype-specific breast cancer detection at early stage

Is the two-bag method viable for DKA treatment?

The two-bag method is both safe and effective for the management of diabetic ketoacidosis (DKA) relative to the one-bag method, a study has shown.

Is the two-bag method viable for DKA treatment?

05 Jan 2025

Vedolizumab after resection helps prevent CD recurrence

For patients with Crohn’s disease (CD) who are scheduled to undergo ileocolonic resection, initiating vedolizumab treatment promptly after the procedure has the potential to prevent recurrence, according to the results of the REPREVIO study.

Vedolizumab after resection helps prevent CD recurrence