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Shorter noninferior to standard acetylcysteine regimen for paracetamol overdose

A shorter acetylcysteine regimen shows similar safety and effectiveness to the standard regimen for moderate paracetamol overdoses ≤30 g, reveals a recent study. This almost halves the duration of treatment required.

Shorter noninferior to standard acetylcysteine regimen for paracetamol overdose

a day ago

COVID-19 vaccines remain effective against severe outcomes

a day ago by

Even as COVID-19 severity wanes and public uptake declines, previous receipt of the 2024-2025 COVID vaccines continues to reduce emergency visits, hospital stays, and deaths among US veterans, as shown in a recent study.

COVID-19 vaccines remain effective against severe outcomes

a day ago

Tirzepatide lowers HbA1c, BMI in youth-onset T2D

16 Oct 2025 by

Once-weekly treatment with tirzepatide significantly reduces HbA_1c levels and BMI in children and adolescents with type 2 diabetes (T2D) compared with placebo, according to the SURPASS-PEDS trial presented at EASD 2025.

Tirzepatide lowers HbA1c, BMI in youth-onset T2D

16 Oct 2025

HPV9 vaccination tied to reduced risk of juvenile idiopathic arthritis

15 Oct 2025

Nine-valent human papillomavirus (HPV9) vaccination may protect against the development of juvenile idiopathic arthritis (JIA), and this benefit persists for at least 3 years, as shown in a retrospective study.

HPV9 vaccination tied to reduced risk of juvenile idiopathic arthritis

15 Oct 2025

GLP-1RA offers protection against mortality, cardiac events for psoriasis patients

15 Oct 2025 by

Patients with psoriasis who are using glucagon-like peptide-1 receptor agonists (GLP-1RAs) appear to have lower risks of mortality and adverse cardiovascular events, according to a retrospective study.

GLP-1RA offers protection against mortality, cardiac events for psoriasis patients

15 Oct 2025

Once-monthly cafraglutide helps with weight loss in adults with obesity

15 Oct 2025

Once-a-month treatment with maridebart cafraglutide—a long-acting peptide–antibody conjugate that combines glucagon-like peptide-1 receptor agonism and glucose-dependent insulinotropic polypeptide receptor antagonism—results in substantial weight reduction in patients with obesity with or without type 2 diabetes, according to a phase II study.

Once-monthly cafraglutide helps with weight loss in adults with obesity

15 Oct 2025

Frontline nelitolimod plus pembrolizumab combo elicits response in advanced melanoma

14 Oct 2025

The toll-like receptor 9 agonist nelitolimod, when combined with pembrolizumab, shows promising antitumour activity in treatment-naïve patients with anti–PD-1/PD-L1 advanced melanoma, according to a phase II open-label trial.

Frontline nelitolimod plus pembrolizumab combo elicits response in advanced melanoma

14 Oct 2025

Extended-release minoxidil pill promotes hair growth in 4 months

14 Oct 2025 by

In patients with androgenetic alopecia, 4 months of treatment with the investigational extended-release oral minoxidil (VDPHL01) appears to induce superior hair growth compared with 6 months of treatment with the topical and immediate-release (IR) formulations, according to the results of a blinded retrospective Investigator Global Assessment (IGA) analysis.

Extended-release minoxidil pill promotes hair growth in 4 months

14 Oct 2025

Delgocitinib cream works wonders in chronic hand eczema

14 Oct 2025 by

Application of delgocitinib cream results in significant improvements in itch, pain, and quality of life (QoL) at week 16 in adults with moderate to severe chronic hand eczema (CHE), as shown in the pooled analysis of the phase III DELTA-1 and -2 trials.

Delgocitinib cream works wonders in chronic hand eczema

14 Oct 2025

High-dose RAS inhibitors reduce kidney failure risk in HF patients

13 Oct 2025

Treatment with high-dose renin-angiotensin system (RAS) inhibitors result in a lower risk of kidney failure in patients with heart failure (HF), reports a study.

High-dose RAS inhibitors reduce kidney failure risk in HF patients

13 Oct 2025

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Shorter noninferior to standard acetylcysteine regimen for paracetamol overdose

Shorter noninferior to standard acetylcysteine regimen for paracetamol overdose

COVID-19 vaccines remain effective against severe outcomes

COVID-19 vaccines remain effective against severe outcomes

Tirzepatide lowers HbA1c, BMI in youth-onset T2D

Tirzepatide lowers HbA1c, BMI in youth-onset T2D

HPV9 vaccination tied to reduced risk of juvenile idiopathic arthritis

HPV9 vaccination tied to reduced risk of juvenile idiopathic arthritis

GLP-1RA offers protection against mortality, cardiac events for psoriasis patients

GLP-1RA offers protection against mortality, cardiac events for psoriasis patients

Once-monthly cafraglutide helps with weight loss in adults with obesity

Once-monthly cafraglutide helps with weight loss in adults with obesity

Frontline nelitolimod plus pembrolizumab combo elicits response in advanced melanoma

Frontline nelitolimod plus pembrolizumab combo elicits response in advanced melanoma

Extended-release minoxidil pill promotes hair growth in 4 months

Extended-release minoxidil pill promotes hair growth in 4 months

Delgocitinib cream works wonders in chronic hand eczema

Delgocitinib cream works wonders in chronic hand eczema

High-dose RAS inhibitors reduce kidney failure risk in HF patients

High-dose RAS inhibitors reduce kidney failure risk in HF patients