News & Updates

Vitamin D implicated in systemic lupus erythematosus

Patients with systemic lupus erythematosus (SLE) with low levels of vitamin D tend to have a more severe form of the disease, according to a systematic review and meta-analysis.

Older paternal age a risk factor for poor reproductive outcomes after ICSI

Paternal age appears to independently factor in the success of intracytoplasmic sperm injection (ICSI), with sperm from men over 45 years of age being associated with increased risk of miscarriage and lower live birth rates, according to a retrospective study.

Coexposure to bisphenols linked to metabolic diseases

A recent study has observed the association of bisphenol A (BPA) and its substitutes with specific metabolic diseases (MDs).

Pregabalin use for noncancer pain linked to increased risk of HF

In the treatment of chronic noncancer pain, the use of pregabalin appears to be associated with a higher incidence of heart failure (HF) when compared with gabapentin, according to a retrospective cohort study.

Natalizumab, ocrelizumab equally effective in multiple sclerosis

In patients with relapsing or progressing multiple sclerosis (MS), clinical outcomes are similar following treatment with natalizumab vs ocrelizumab, according to a retrospective study.

Outcomes after sleeve gastrectomy differ across race, ethnicities

Glycaemic outcomes following sleeve gastrectomy (SG) vary by race and ethnicity, with non-Hispanic Black (NHB) participants showing less favourable outcomes, reports a study.

Clozapine use tied to increased infection risk in schizophrenia

Among patients receiving treatment for schizophrenia, infections appear to occur at a higher rate with clozapine vs olanzapine, as shown in a study from Hong Kong.

GLP-1RAs may provide migraine relief independent of weight loss

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have the potential to reduce the frequency of migraines even in patients who do not lose weight—an effect that may be related to a reduction in intracranial pressure, according to a pilot prospective observational study.

Cataracts may raise risk of fractures

Individuals with cataracts are more likely to experience fractures than those without the condition, suggests a study. However, people who have undergone cataract surgery appear to have a significantly lower fracture risk, offering a potential protective effect.

A closer look at the safety profile of sitagliptin