News & Updates

Reusable noninferior to single-use catheters for patients with urinary retention

For patients with urinary retention requiring clean intermittent catheterization, the use of reusable catheters does not appear to increase the risk of urinary tract infection (UTI) and serious complications when compared with single-use catheters, according to a noninferiority randomized clinical trial.

Online as good as in-person care for atopic dermatitis

An online, team-based connected health (TCH) model of care does not appear to be any different than in-person care in terms of improving outcomes in patients with atopic dermatitis (AD), according to a study.

PSA screening in mainland China and HK highly cost-effective, may improve prostate cancer survival

A microsimulation study conducted by researchers from the University of Hong Kong (HKU), Guangzhou Medical University, and Shanghai Jiao Tong University shows that prostate-specific antigen (PSA) screening would be highly cost-effective and significantly improve survival outcomes for patients with prostate cancer in China.

Semaglutide associated with reduced ICH risk in LVO treated with reperfusion therapy

Moderate drinking may lower risk of severe PAD, but only for nonsmokers

Alcohol consumption and cigarette smoking interact to modify the risk of chronic limb-threatening ischaemia (CLTI), the most severe form of peripheral arterial disease (PAD) in a local cohort, as suggested in a study. Specifically, low-to-moderate drinking is protective among individuals who do not smoke, whereas any level of drinking contributes to a risk increase among smokers.

Ustekinumab Q4W dosing induces response, remission in children with moderate-to-severe UC

Paediatric patients with moderately to severely active ulcerative colitis (UC) show a favourable response to ustekinumab administered once every 4 weeks (Q4W), according to a study. This results in greater clinical response and remission associated with higher serum drug levels.

Air pollution exposure a risk factor for late-onset rheumatoid arthritis

Exposure to fine particulate matter (PM) appears to contribute to an increased risk of rheumatoid arthritis incidence after age 65 years, as shown in a study.

Novel SYK inhibitor elicits durable Hb response in autoimmune haemolytic anaemia

The highly selective oral spleen tyrosine kinase (SYK) inhibitor sovleplenib has demonstrated significant clinical benefit in patients with warm autoimmune haemolytic anaemia (wAIHA), with durable haemoglobin (Hb) response and a favourable safety profile, as shown in the phase III ESLIM-02 trial.

Fenfluramine works in paediatric, adult patients with developmental/epileptic encephalopathies

In children and adults with developmental and epileptic encephalopathies (DEEs), treatment with fenfluramine appears to be effective with predictable tolerability, as shown in a real-world study.