News &amp; Updates

Among older adults who are undergoing major elective surgery, those who are overweight may have lower mortality after the procedure compared with those who have normal weight, as suggested in a study.

Being overweight may protect against mortality following surgery in older adults

Risk factors for progression in Asians with early-stage CKD identified in study

Underlying medical conditions, albuminuria, ethnicity, lifestyle, and medication all factor into the risk of progression in a multiethnic Asian population of patients with early-stage chronic kidney disease (CKD), as shown in a study from Singapore.

Risk factors for progression in Asians with early-stage CKD identified in study

Enzalutamide plus radium-223 improves rPFS in mCRPC

First-line treatment with enzalutamide plus radium-223 (Ra223) results in significant improvements in radiological progression-free survival (rPFS) in patients with metastatic castration-resistant prostate cancer (mCRPC), results of the EORTC 1222/PEACE-3 trial have shown.

Enzalutamide plus radium-223 improves rPFS in mCRPC

12 Sep 2025

TALENTACE supports atezolizumab + bevacizumab after TACE for HCC

Findings from the TALENTACE trial presented at ESMO GI 2025 support the combination of atezolizumab and bevacizumab after transarterial chemoembolization (TACE) for the treatment of individuals with systemically untreated, intermediate-to-high tumour burden, unresectable hepatocellular carcinoma (HCC).

TALENTACE supports atezolizumab + bevacizumab after TACE for HCC

12 Sep 2025

Vericiguat misses endpoint in HFrEF trial

In the treatment of patients with heart failure and reduced ejection fraction (HFrEF) and no recent worsening, the use of vericiguat falls short of reducing the risk of the composite of cardiovascular death and HF hospitalization, as shown in a phase III study.

Vericiguat misses endpoint in HFrEF trial

Hydrogen–oxygen therapy alleviates sleep disorders and improves mood

Inhalation of a low-dose mixture of hydrogen and oxygen effectively improves sleep quality and mood through its antioxidant properties, by reducing wake time, enhancing sleep quality and relieving psychological stress, a Chinese study has found.

Hydrogen–oxygen therapy alleviates sleep disorders and improves mood

Increased risk of stroke in possible sarcopenia patients with fall history

The risk of incident stroke in middle-aged and older patients with possible sarcopenia (PS) is higher in those with fall history than those without, according to the first study to establish fall history as a long-term stroke predictor in Asian PS cohorts.

Increased risk of stroke in possible sarcopenia patients with fall history

Sleep disordered breathing prevalent in hypertrophic cardiomyopathy

A significant number of patients with hypertrophic cardiomyopathy (HCM) also have sleep disordered breathing (SDB), which is linked to more severe heart problems, according to a study.

Sleep disordered breathing prevalent in hypertrophic cardiomyopathy

Oral pharmaceutical LSD formulation beneficial in generalized anxiety disorder

11 Sep 2025 by

A single administration of MM120, a semisynthetic pharmaceutical formulation of lysergic acid diethylamide (LSD), helps ease symptoms in patients with moderate to severe generalized anxiety disorder (GAD), as shown in a phase IIB study.

Oral pharmaceutical LSD formulation beneficial in generalized anxiety disorder

Liver-related events, cardiovascular outcomes elevated in steatotic liver disease patients

Individuals with steatotic liver disease are at an increased risk of developing liver-related events, liver cancer, and cardiovascular outcomes, reveals a study.

Liver-related events, cardiovascular outcomes elevated in steatotic liver disease patients