How do ARTs affect body composition in children living with HIV?
In children living with HIV, treatment with dolutegravir and atazanavir/ritonavir (ATV/r) appear to yield greater gains in fat-free mass and muscle mass compared with lopinavir/ritonavir (LPV/r), a study has shown. By contrast, darunavir/ritonavir (DRV/r), tenofovir alafenamide (TAF), and prior exposure to nevirapine are associated with gains in fat mass.
