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Naltrexone–bupropion a safe weight-loss treatment for persons with obesity, depression

08 May 2026 by

The extended-release combination of naltrexone and bupropion (NB-ER) may be used as safe and effective treatment for weight reduction among individuals with overweight/obesity and mild to moderate symptoms of depression, suggests a study.

Naltrexone–bupropion a safe weight-loss treatment for persons with obesity, depression

08 May 2026

Vemircopan holds little benefit in generalized myasthenia gravis

08 May 2026

The oral, selective factor D inhibitor vemircopan falls short of meeting the prespecified threshold for efficacy in the treatment of generalized myasthenia gravis, as shown in a phase 2 trial.

Vemircopan holds little benefit in generalized myasthenia gravis

08 May 2026

Esketamine, rTMS and ECT: Which is more cost-effective in treatment-resistant depression?

08 May 2026 by

Esketamine is more cost-effective than transcranial magnetic stimulation (rTMS) and electroconvulsive therapy (ECT), but not when compared with other commonly used third-line treatments for treatment-resistant depression (TRD) in Hong Kong, a multi-armed modelling study has shown.

Esketamine, rTMS and ECT: Which is more cost-effective in treatment-resistant depression?

08 May 2026

Healthy lifestyle helps preserve intrinsic capacity in older adults

07 May 2026 by

Older adults who adhere to healthy lifestyle behaviours appear to have fewer intrinsic capacity deficits, according to local research.

Healthy lifestyle helps preserve intrinsic capacity in older adults

07 May 2026

Weight loss enhances life quality in people with obesity

07 May 2026

Individuals with obesity may improve their health-related quality of life (HRQoL) by losing weight, suggests a study.

Weight loss enhances life quality in people with obesity

07 May 2026

Ageing population drives surge in ED admissions in SG

07 May 2026 by

Admissions to the emergency department (ED) increased from 2008 to 2019 in Singapore, particularly in the older adult population, reports a study.

Ageing population drives surge in ED admissions in SG

07 May 2026

PCE predicts ocular diseases using primary care data

07 May 2026

The single composite metric Pooled Cohort Equations (PCE) helps identify the risk for multiple ocular diseases using data readily available in primary care, a study has shown.

PCE predicts ocular diseases using primary care data

07 May 2026

Prolonged grief common in youths after parent or sibling loss to cancer

07 May 2026 by

Individuals who have lost a parent or sibling to cancer at a young age may experience grief-related symptoms for a prolonged period, with a more pronounced effect after sibling loss, according to a review and meta-analysis.

Prolonged grief common in youths after parent or sibling loss to cancer

07 May 2026

Branebrutinib makes no difference in RA management

07 May 2026

A phase 2a trial of rheumatoid arthritis (RA) has shown no significant difference between the investigational branebrutinib and placebo in terms of clinical efficacy, despite the drug having a favourable safety profile.

Branebrutinib makes no difference in RA management

07 May 2026

Sacituzumab tirumotecan boosts survival in advanced EGFRm NSCLC

07 May 2026 by

Treatment with sacituzumab tirumotecan (sac-TMT) significantly improves progression-free survival (PFS) and overall survival (OS) in patients with previously treated advanced EGFR-mutated (EGFRm) non-small cell lung cancer (NSCLC) compared with docetaxel, according to the OptiTROP-Lung03 study presented at ELCC 2026.

Sacituzumab tirumotecan boosts survival in advanced EGFRm NSCLC

07 May 2026

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Naltrexone–bupropion a safe weight-loss treatment for persons with obesity, depression

Naltrexone–bupropion a safe weight-loss treatment for persons with obesity, depression

Vemircopan holds little benefit in generalized myasthenia gravis

Vemircopan holds little benefit in generalized myasthenia gravis

Esketamine, rTMS and ECT: Which is more cost-effective in treatment-resistant depression?

Esketamine, rTMS and ECT: Which is more cost-effective in treatment-resistant depression?

Healthy lifestyle helps preserve intrinsic capacity in older adults

Healthy lifestyle helps preserve intrinsic capacity in older adults

Weight loss enhances life quality in people with obesity

Weight loss enhances life quality in people with obesity

Ageing population drives surge in ED admissions in SG

Ageing population drives surge in ED admissions in SG

PCE predicts ocular diseases using primary care data

PCE predicts ocular diseases using primary care data

Prolonged grief common in youths after parent or sibling loss to cancer

Prolonged grief common in youths after parent or sibling loss to cancer

Branebrutinib makes no difference in RA management

Branebrutinib makes no difference in RA management

Sacituzumab tirumotecan boosts survival in advanced EGFRm NSCLC

Sacituzumab tirumotecan boosts survival in advanced EGFRm NSCLC