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Cabozantinib plus atezolizumab improves PFS in mCRPC after progression on ARPI

20 Jun 2025

In the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) with extrapelvic soft-tissue metastases that has progressed on an androgen receptor pathway inhibitor (ARPI), the combination of cabozantinib plus atezolizumab appears to prolong progression-free survival (PFS), according to data from the open-label phase 3 CONTACT-02 trial.

Cabozantinib plus atezolizumab improves PFS in mCRPC after progression on ARPI

20 Jun 2025

Glucose-lowering med shows promise for treating kidney stones in nondiabetics

17 Jun 2025 by

Treatment with the sodium-glucose cotransporter 2 (SGLT2) inhibitor empagliflozin helps improve the urinary lithogenic risk profile of nondiabetic patients with calcium and uric acid stones, as shown in the results of the randomized crossover SWEETSTONE trial.

Glucose-lowering med shows promise for treating kidney stones in nondiabetics

17 Jun 2025

Low-carb, animal fat/protein-heavy diet poses increased bladder cancer risk

12 Jun 2025 by

A low-carbohydrate diet (LCD), particularly when its fat and protein sources are predominantly animal-based, may contribute to increased risk of bladder cancer among Chinese Singaporeans, according to new research.

Low-carb, animal fat/protein-heavy diet poses increased bladder cancer risk

12 Jun 2025

Differences in pelvic floor anatomy may explain UI in female athletes

08 Jun 2025

Urinary incontinence in nulliparous female elite athletes may have multifactorial aetiology, as shown by differences seen in dynamic pelvic MRI, reports a study.

Differences in pelvic floor anatomy may explain UI in female athletes

08 Jun 2025

Mind over bladder: Mindfulness, zap therapy help with situational urge incontinence

07 Jun 2025 by

Noninvasive approaches such as mindfulness training and transcranial direct current stimulation (tDCS) hold therapeutic potential in women with situational urgency urinary incontinence (UUI), as shown in a study.

Mind over bladder: Mindfulness, zap therapy help with situational urge incontinence

07 Jun 2025

Gemcitabine for IR-NMIBC tied to more recurrence vs BCG

06 Jun 2025 by

Treatment-naive patients with immediate-risk (IR) nonmuscle-invasive bladder cancer (NMIBC) who received gemcitabine appear to have greater recurrence risk than those given Bacillus Calmette-Guerin (BCG). Both treatments, however, are effective against disease progression.

Gemcitabine for IR-NMIBC tied to more recurrence vs BCG

06 Jun 2025

Nerve-sparing technique preserves erectile function after RARP

13 May 2025 by

A nerve-sparing technique decreases erectile dysfunction in men undergoing robot-assisted radical prostatectomy (RARP) for prostate cancer in a phase III study.

Nerve-sparing technique preserves erectile function after RARP

13 May 2025

Rectal spacer relieves GI issues following RT for prostate cancer

08 May 2025 by

In a large retrospective study, the incidence of bowel disorders and related procedures dropped when a polyethylene glycol-based hydrogel spacer (PHS) was used in men undergoing radiotherapy (RT) for prostate cancer.

Rectal spacer relieves GI issues following RT for prostate cancer

08 May 2025

Which factors predict regret after urinary reconstruction in spinal cord injury patients?

06 May 2025

Lower urinary tract reconstruction remains a well-accepted approach for managing refractory neurogenic bladder in patients with spinal cord injury, but decision regret persists for some.

Which factors predict regret after urinary reconstruction in spinal cord injury patients?

06 May 2025

More than half of UTIs treated inappropriately in primary care in SG

05 May 2025 by

New research from Singapore has shown that most patients with uncomplicated urinary tract infections (UTIs) being treated in primary care receive inappropriate antibiotics.

More than half of UTIs treated inappropriately in primary care in SG

05 May 2025

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Cabozantinib plus atezolizumab improves PFS in mCRPC after progression on ARPI

Cabozantinib plus atezolizumab improves PFS in mCRPC after progression on ARPI

Glucose-lowering med shows promise for treating kidney stones in nondiabetics

Glucose-lowering med shows promise for treating kidney stones in nondiabetics

Low-carb, animal fat/protein-heavy diet poses increased bladder cancer risk

Low-carb, animal fat/protein-heavy diet poses increased bladder cancer risk

Differences in pelvic floor anatomy may explain UI in female athletes

Differences in pelvic floor anatomy may explain UI in female athletes

Mind over bladder: Mindfulness, zap therapy help with situational urge incontinence

Mind over bladder: Mindfulness, zap therapy help with situational urge incontinence

Gemcitabine for IR-NMIBC tied to more recurrence vs BCG

Gemcitabine for IR-NMIBC tied to more recurrence vs BCG

Nerve-sparing technique preserves erectile function after RARP

Nerve-sparing technique preserves erectile function after RARP

Rectal spacer relieves GI issues following RT for prostate cancer

Rectal spacer relieves GI issues following RT for prostate cancer

Which factors predict regret after urinary reconstruction in spinal cord injury patients?

Which factors predict regret after urinary reconstruction in spinal cord injury patients?

More than half of UTIs treated inappropriately in primary care in SG

More than half of UTIs treated inappropriately in primary care in SG