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Oral as good as extended-release injectable naltrexone for hospitalized adults with AUD

11 May 2025

For hospitalized individuals initiating treatment for alcohol use disorder (AUD), oral naltrexone is equally efficacious as the extended-release injectable formulation in terms of reducing heavy drinking days, as shown in a study.

Oral as good as extended-release injectable naltrexone for hospitalized adults with AUD

11 May 2025

Anticholinergic burden promotes poor cognition in psychosis patients

07 May 2025 by

Anticholinergic burden appears to worsen cognitive functioning among patients with psychosis, but reducing the use of anticholinergic medication helps improve cognition, suggests a study.

Anticholinergic burden promotes poor cognition in psychosis patients

07 May 2025

Testosterone may protect against effects of gender-related discrimination

06 May 2025

Testosterone appears to provide protective benefits against the negative impact of gender-related discrimination on well-being among LGBTQ+ individuals, suggests a recent study.

Testosterone may protect against effects of gender-related discrimination

06 May 2025

Mental health issues may persist after gender-affirming surgery

05 May 2025

Gender-affirming surgery is associated with an increase in the risk of mental health issues among transgender people, reveals a study.

Mental health issues may persist after gender-affirming surgery

05 May 2025

Exercise therapy plus family intervention beneficial to children with ADHD

05 May 2025

Children with attention deficit and hyperactivity disorder (ADHD) who undergo exercise therapy combined with family intervention appear to show improvements in attention and executive function, social functioning, and school performance, according to a retrospective cohort study.

Exercise therapy plus family intervention beneficial to children with ADHD

05 May 2025

Anxiety, depression predict pain, HRQoL in cirrhosis patients

03 May 2025

Pain is prevalent among patients with cirrhosis who are undergoing liver transplant evaluation, a study has found. Anxiety and depression show a significant association with pain and appear to predict poor health-related quality of life (HRQoL) in this population.

Anxiety, depression predict pain, HRQoL in cirrhosis patients

03 May 2025

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-April-2025

02 May 2025

New drug applications approved by US FDA as of 1-15 April 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-April-2025

02 May 2025

Childhood adversity predicts psychosis onset

30 Apr 2025

Children who have been exposed to early adversities are at increased odds of developing psychosis, suggests a study.

Childhood adversity predicts psychosis onset

30 Apr 2025

Esketamine combined with SSRI or SNRI leads to different outcomes in treatment-resistant depression

30 Apr 2025 by

Esketamine combined with a serotonin-norepinephrine reuptake inhibitor (SNRI) reduces rates of mortality, hospitalizations, and depressive relapses, while esketamine combined with a selective serotonin reuptake inhibitor (SSRI) decreases the incidence of suicidal attempts, a real-world comparative effectiveness study on treatment-resistant depression (TRD) has shown.

Esketamine combined with SSRI or SNRI leads to different outcomes in treatment-resistant depression

30 Apr 2025

Long-term D2 blockade not to blame for relapse in schizophrenia

29 Apr 2025

Continuous dopamine D2 receptor blockade does not appear to increase the risk of breakthrough psychosis in patients with first-episode schizophrenia, as shown in a study.

Long-term D2 blockade not to blame for relapse in schizophrenia

29 Apr 2025

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Oral as good as extended-release injectable naltrexone for hospitalized adults with AUD

Oral as good as extended-release injectable naltrexone for hospitalized adults with AUD

Anticholinergic burden promotes poor cognition in psychosis patients

Anticholinergic burden promotes poor cognition in psychosis patients

Testosterone may protect against effects of gender-related discrimination

Testosterone may protect against effects of gender-related discrimination

Mental health issues may persist after gender-affirming surgery

Mental health issues may persist after gender-affirming surgery

Exercise therapy plus family intervention beneficial to children with ADHD

Exercise therapy plus family intervention beneficial to children with ADHD

Anxiety, depression predict pain, HRQoL in cirrhosis patients

Anxiety, depression predict pain, HRQoL in cirrhosis patients

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-April-2025

Original-New-Drug-Application-Approvals-by-US-FDA--1-15-April-2025

Childhood adversity predicts psychosis onset

Childhood adversity predicts psychosis onset

Esketamine combined with SSRI or SNRI leads to different outcomes in treatment-resistant depression

Esketamine combined with SSRI or SNRI leads to different outcomes in treatment-resistant depression

Long-term D2 blockade not to blame for relapse in schizophrenia

Long-term D2 blockade not to blame for relapse in schizophrenia