News & Updates

Efruxifermin reduces fibrosis in MASH cirrhosis

The long-acting, bivalent fibroblast growth factor 21 analogue efruxifermin reduced fibrosis at 96 weeks in patients with compensated cirrhosis due to metabolic dysfunction-associated steatohepatitis (MASH) in the phase 2b SYMMETRY trial.

Autism spectrum disorder tied to heightened risk of Parkinson’s disease

Individuals with autism spectrum disorder face an increased risk of Parkinson’s disease (PD), independent of depression or antidepressant use and antipsychotic exposure, according to a nationwide population-based prospective cohort study.

Dapagliflozin Catania SGLT2i

Prenatal triptan exposure unlikely to harm neurodevelopmental outcomes in children

Maternal use of the migraine drug triptans before or during pregnancy does not appear to put infants at risk of developing neurodevelopmental disorders, according to a study.

Differences in pelvic floor anatomy may explain UI in female athletes

Urinary incontinence in nulliparous female elite athletes may have multifactorial aetiology, as shown by differences seen in dynamic pelvic MRI, reports a study.

GLP1-RA treatment not harmful to mental health

In the treatment of patients with overweight/obesity and/or diabetes, glucagon-like peptide 1 receptor agonists (GLP1-RAs) do not increase the risk of psychiatric adverse events or worsen depressive symptoms but rather confer improvements in quality of life (QOL) and eating behaviour, according to the results of a meta-analysis.

Mind over bladder: Mindfulness, zap therapy help with situational urge incontinence

Noninvasive approaches such as mindfulness training and transcranial direct current stimulation (tDCS) hold therapeutic potential in women with situational urgency urinary incontinence (UUI), as shown in a study.

HAS-BLED outclasses DOAC, ORBIT scores in predicting bleeding in nonvalvular AF

In patients with nonvalvular atrial fibrillation (AF), the best predictor of major bleeding was the HAS-BLED score, demonstrating similar efficacy to the DOAC score and superiority to the ORBIT score, suggests a China study.

Multiple antibiotic exposures in early life may have long-term respiratory consequences

Preterm infants with multiple episodes of antibiotic exposure prenatally have a higher likelihood of having impaired lung function at early school age, as shown in a study.

Eye diseases prevalent among CKD patients in SG

Patients with chronic kidney disease (CKD) have a particularly high burden of eye diseases, including diabetic retinopathy (DR) and age-related macular degeneration (AMD), despite receiving regular medical follow-up, as shown in a study from Singapore.