News &amp; Updates

Adipose tissue content of linoleic acid displays an inverse relationship with all-cause death, while that of arachidonic acid is associated with higher all-cause mortality, reveals a study.

Adipose tissue content of fatty acids linked to mortality

Adjunctive vagus nerve stimulation helps reduce seizure frequency

Vagus nerve stimulation (VNS) as an adjunctive treatment appears to lessen the frequency of generalized tonic–clonic seizures (GTCS) by 77 percent over 24 months, as shown in a study.

Adjunctive vagus nerve stimulation helps reduce seizure frequency

Having a patient with recurrent infections? It might be immunodeficiency.

16 Apr 2025 by

Recurring infections, especially in children, may be a sign of an underlying immune deficiency rather than just frequent illness, says an expert.

Having a patient with recurrent infections? It might be immunodeficiency.

Maternal fat intake at pregnancy tied to higher offspring weight

Pregnant women with increased fat intake, particularly trans fat, are more likely to deliver offspring with a higher body weight, suggests a study. Consumption of other macronutrients from various food sources, however, does not appear to affect offspring weight.

Maternal fat intake at pregnancy tied to higher offspring weight

Novel PCSK9 inhibitor for high cholesterol passes phase II trial

A recent trial presented at ACC.25 has demonstrated the efficacy of AZD0780 in reducing low-density lipoprotein cholesterol (LDL-C) in patients with hypercholesterolemia, with a favourable safety and tolerability profile.

Novel PCSK9 inhibitor for high cholesterol passes phase II trial

Does CKD reduce tirzepatide benefits on HFpEF patients with obesity?

Long-term treatment with tirzepatide results in improved renal function in patients with heart failure with preserved ejection fraction (HFpEF) and obesity, regardless of the absence or presence of chronic kidney disease (CKD), according to a post hoc analysis of the SUMMIT trial presented at ACC.25.

Does CKD reduce tirzepatide benefits on HFpEF patients with obesity?

15 Apr 2025

TB vax primer augments BCG-induced immune response in bladder cancer patients

Initial results of the phase I RUTIVAC-1 study show the potential of two doses of a tuberculosis (TB) vaccine given after surgery but before standard BCG* treatment to boost immunity and reduce the odds of recurrence in patients with non-muscle-invasive bladder cancer (NMIBC).

TB vax primer augments BCG-induced immune response in bladder cancer patients

15 Apr 2025

Gradual adalimumab tapering minimizes uveitis recurrence in children

In children with noninfectious uveitis being treated with adalimumab, tapering speed appears to affect the risk of relapse, with a slow, gradual approach emerging as the optimal strategy, according to a multicentre retrospective cohort study.

Gradual adalimumab tapering minimizes uveitis recurrence in children

Oral semaglutide reduces CV risk in T2D patients

Once-daily treatment with oral semaglutide, a GLP-1* receptor agonist, significantly reduced the risk of major adverse cardiovascular events (MACE) in patients with type 2 diabetes (T2D) and established atherosclerotic cardiovascular disease (ASCVD) and/or chronic kidney disease (CKD), according to the SOUL** trial presented at ACC.25.

Oral semaglutide reduces CV risk in T2D patients