News & Updates

Diabetes mellitus is a growing health problem traditionally characterized by peripheral insulin resistance (IR), increased he
Diabetes mellitus is a growing health problem traditionally characterized by peripheral insulin resistance (IR), increased hepatic gluconeogenesis, and impaired pancreatic beta-cell function. However, the pathophysiology of T2DM is complex, and disease progression is linked to factors beyond insulin dysregulation and reduced first-phase insulin response.
02 Aug 2023 byJoanne G. Blanco, MD

Diabetes mellitus is a growing health problem traditionally characterized by peripheral insulin resistance (IR), increased hepatic gluconeogenesis, and impaired pancreatic beta-cell function.1 However, the pathophysiology of T2DM is complex, and disease progression is linked to factors beyond insulin dysregulation and reduced first-phase insulin response.2 Unfortunately, many existing anti-hyperglycemic medications cause side effects such as hypoglycemia and weight gain, which may reduce adherence to treatment. In contrast, ideal diabetes medications would control glycemia without a risk of hypoglycemia, while providing additional beneficial effects on beta-cell function, body weight, lipid profiles, hypertension and cardiovascular risk.3

Diabetes mellitus is a growing health problem traditionally characterized by peripheral insulin resistance (IR), increased hepatic gluconeogenesis, and impaired pancreatic beta-cell function. However, the pathophysiology of T2DM is complex, and disease progression is linked to factors beyond insulin dysregulation and reduced first-phase insulin response.
02 Aug 2023
Physical activity offsets downsides of abnormal sleep duration
Physical activity offsets downsides of abnormal sleep duration
01 Aug 2023 byAudrey Abella

Short and long sleep durations were tied to higher risks for all-cause, cardiovascular disease (CVD), and cancer mortality, but these may be attenuated by engaging in physical activity (PA), a population-based cohort study suggests.

Physical activity offsets downsides of abnormal sleep duration
01 Aug 2023