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ARANOTE: Darolutamide plus ADT delays progression in mHSPC
28 Feb 2025
byStephen Padilla
The use of darolutamide (DARO) in addition to androgen deprivation therapy (ADT) is effective at improving radiological progression-free survival (rPFS) in patients with metastatic hormone-sensitive prostate cancer (mHSPC) compared with placebo plus ADT, irrespective of disease volume, according to the subanalysis of the phase III ARANOTE trial.
ARANOTE: Darolutamide plus ADT delays progression in mHSPC
28 Feb 2025
Mevrometostat plus enzalutamide improves outcomes in mCRPC patients
27 Feb 2025
byStephen Padilla
Treatment with mevrometostat (MEV), an enhancer of zeste homolog 2 inhibitor, in combination with enzalutamide (ENZ) results in better survival outcomes and response than ENZ alone among patients with metastatic castration-resistant prostate cancer (mCRPC), reports a study presented at ASCO GU 2025. The combined therapy also demonstrates a favourable safety profile.