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SC dose escalation restores efficacy of infliximab in IBD patients
17 Feb 2025
byStephen Padilla
Escalating the dose of subcutaneous (SC) CT-P13, a biosimilar of infliximab, from 120 to 240 mg every 2 weeks appears to bring back the efficacy of the drug in patients with inflammatory bowel disease (IBD) who no longer respond to treatment, suggests a study presented at 2025 Crohn's & Colitis Congress.
SC dose escalation restores efficacy of infliximab in IBD patients
17 Feb 2025
DOACs for ICH survivors with atrial fibrillation? Stroke protection comes at a cost
14 Feb 2025
byJairia Dela Cruz
For survivors of intracerebral haemorrhage (ICH) with atrial fibrillation (AF), the use of direct oral anticoagulants (DOACs) works to prevent ischaemic stroke events, but this benefit appears to be offset by major bleeding side effects, as shown in the open-label, phase III PRESTIGE-AF trial.