News & Updates

What’s new in advanced urothelial carcinoma?

Enfortumab vedotin and pembrolizumab’s (EV+P) EV-302 trial results represent a major advancement in metastatic urothelial carcinoma (mUC), including in Asian patients, according to Professor Ravindran Kanesvaran of the National Cancer Centre in Singapore, who also discussed managing skin toxicity associated with this regimen and provided an overview of other agents for UC under investigation at Uro-Oncology Asia 2025.

Better NPC risk stratification with identification of distinct EBV DNA molecular features

A research team from the Faculty of Medicine, Chinese University of Hong Kong (CUHK) has identified molecular features in Epstein-Barr virus (EBV) DNA specifically associated with nasopharyngeal cancer (NPC) that differ significantly from the EBV DNA found in individuals with general EBV infections.

Microultrasonography a promising alternative to MRI for image-guided prostate biopsy

Microultrasonography-guided biopsy performs similarly as MRI/conventional ultrasonography fusion-guided biopsy in terms of detecting Gleason Grade Group 2 or higher prostate cancer in biopsy-naïve men, according to the results of the multicentre, international OPTIMUM study.

How to optimize treatment strategies for mHSPC by integrating pivotal data?

Sitting less, being more active can add years of life to postmenopausal cancer survivors

New research suggests that increasing daily step count and engaging in physical activity while reducing sitting time may reduce the risk of death from all cause and from cardiovascular disease (CVD) among postmenopausal women with a history of cancer.

Neoadjuvant chemoimmunotherapy beneficial in locally advanced ESCC

In the treatment of locally advanced esophageal squamous cell carcinoma (ESCC), neoadjuvant chemoimmunotherapy may prolong overall and disease-free survival compared with neoadjuvant chemoradiotherapy, according to a study from China.

Study: Replace butter with plant-based oils for longevity

Using plant-based oils such as olive, soybean, or canola instead of butter may help prevent premature deaths, as reported in a large study.

Alternating R-DA-EDOCH/R-DHAP induces deep remission in young Chinese patients with MCL

A phase III trial demonstrated a high minimal residual disease (MRD)-negativity rate with intensive continuous dose-adjusted rituximab plus etoposide, dexamethasone, doxorubicin, cyclophosphamide, and vincristine (R-DA-EDOCH) alternated with rituximab, dexamethasone, cytarabine, and cisplatin (R-DHAP), thereby offering an alternative induction therapy choice for young Chinese patients with mantle-cell lymphoma (MCL).

Curcumin reduces vincristine-induced neuropathy in paediatric ALL

A double-blind randomized controlled trial (RCT) reports a significantly lower incidence of vincristine-induced peripheral neuropathy (VIPN) in paediatric acute lymphoblastic leukaemia (ALL) patients who received curcumin vs placebo.