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Schizophrenia: Clozapine a better fit for second relapse prevention
06 Feb 2025
byKanas Chan
A population-based cohort study in Finland has revealed that clozapine initiation after a first-episode schizophrenia relapse is associated with a lower risk of second relapse compared with continuation with the same antipsychotic or switching to another non-clozapine oral antipsychotic. These findings challenge current guidelines that recommend clozapine as a third-line treatment.