News &amp; Updates

Three dual combinations of commonly prescribed antihypertensives – amlodipine and perindopril, perindopril and indapamide, or amlodipine and indapamide – demonstrated equal blood pressure (BP)-lowering efficacy among Indian adults, according to the results of the TOPSPIN trial presented at AHA 2024.

TOPSPIN highlights three dual combo pills for BP control

10 Dec 2024

$Gabapentinoids may raise risk of hip fractures$

Gabapentinoids may raise risk of hip fractures

Use of gabapentinoids appears to contribute to an increase in the risk of hip fractures, especially for patients who are frail or have chronic kidney disease (CKD), according to a study.

Gabapentinoids may raise risk of hip fractures

Microbiome-based noninvasive diagnostic tool now available for IBD

Researchers at the Chinese University of Hong Kong (CUHK) have developed a microbiome-based noninvasive diagnostic tool for inflammatory bowel disease (IBD), which received a silver medal at the Geneva International Exhibition of Inventions 2024.

Microbiome-based noninvasive diagnostic tool now available for IBD

Nirmatrelvir-ritonavir efficacy and risk factors for COVID-19 hospitalization

The post-pandemic burden of COVID-19 remains significant in adults. Four studies from IDWeek 2024 highlight the benefits of nirmatrelvir-ritonavir (NMV/r) for high-risk adults with SARS-CoV-2 immunity and link chronic conditions to COVID-19 hospitalization. Identifying high-risk patients and using NMV/r in outpatient settings can reduce severe outcomes.

Nirmatrelvir-ritonavir efficacy and risk factors for COVID-19 hospitalization

EVT outcomes poorer in ischaemic stroke patients ≥80 years old

Outcomes after endovascular thrombectomy (EVT) in patients ≥80 years old were significantly worse than those in their younger counterparts, a Hong Kong stroke centre study has found.

EVT outcomes poorer in ischaemic stroke patients ≥80 years old

CV risk and obesity associated with reduced brain volume earlier in males than females

The detrimental influence of cardiovascular (CV) risk and obesity on grey matter volume impacts males a decade earlier than females, a recent UK study has found.

CV risk and obesity associated with reduced brain volume earlier in males than females

BPaLM regimen looks good for drug-resistant TB in children, adults

09 Dec 2024 by

A therapeutic regimen comprising bedaquiline, pretomanid, linezolid, and moxifloxacin (BPaLM) appears to work against drug-resistant tuberculosis (TB) both in paediatric and adult patients, according to two small studies conducted in Indonesia.

BPaLM regimen looks good for drug-resistant TB in children, adults

Sexual dysfunction prevalent in women with rheumatoid arthritis

Nearly half of women with rheumatoid arthritis (RA) experience female sexual dysfunction (FSD), suggesting a link between FSD risk and RA, according to the results of a systematic review and meta-analysis. Menopause and depression status also significantly correlate with FSD in women with RA.

Sexual dysfunction prevalent in women with rheumatoid arthritis

09 Dec 2024

Which instruments measure homework adherence in MBCT for FSD?

09 Dec 2024 by

There appears to be no gold standard instrument used in assessing homework adherence among patients undergoing mindfulness-based cognitive therapy (MBCT) interventions for female sexual dysfunction (FSD), reports a study. However, some instruments with psychometric evidence may be used by clinicians to monitor homework adherence.

Which instruments measure homework adherence in MBCT for FSD?

Is epididymal cyst lesion linked to impaired semen parameters in men?

No association exists between semen parameters and epididymal cyst lesions (ECLs), which include both spermatoceles and epididymal cysts, among men presenting for fertility evaluation, a study has shown.

Is epididymal cyst lesion linked to impaired semen parameters in men?