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Glucose level affects immunotherapy efficacy in NSCLC

A study from Israel presented at ELCC 2026 supports the role of glucose control as a modifiable host factor that could improve the effectiveness of immune checkpoint inhibitors in the treatment of non-small cell lung cancer (NSCLC).

Glucose level affects immunotherapy efficacy in NSCLC

1 hour ago

Mycophenolate mofetil as good as methotrexate for juvenile localized scleroderma

5 hours ago

In the treatment of patients with juvenile localized scleroderma, mycophenolate mofetil compares favourably with methotrexate in terms of reducing clinical activity and flare rate, according to a retrospective study.

Mycophenolate mofetil as good as methotrexate for juvenile localized scleroderma

5 hours ago

Pimicotinib for tenosynovial giant cell tumour hits targets in pivotal trial

21 hours ago by

The highly selective colony-stimulating factor-1 receptor inhibitor pimicotinib demonstrates robust antitumour activity in patients with tenosynovial giant cell tumour, yielding meaningful improvements in physical function and symptom burden with a manageable safety profile, according to the international phase III MANEUVER trial.

Pimicotinib for tenosynovial giant cell tumour hits targets in pivotal trial

21 hours ago

GLP-1 RAs lower risk of liver-related outcomes, death in patients with harmful alcohol use

23 hours ago

Using glucagon-like peptide-1 receptor agonists (GLP-1 RAs) may reduce the risk of liver outcomes, death, and harmful alcohol use in patients with alcohol use disorder, reveals a study.

GLP-1 RAs lower risk of liver-related outcomes, death in patients with harmful alcohol use

23 hours ago

One-time screening in never-smokers a game-changer in lung cancer

a day ago by

Data from a large, prospective, non-randomized study in China show that one-time low-dose computed tomography (LDCT) screening is associated with a significant reduction in lung cancer mortality in a non–risk-based population, including those who have never smoked.

One-time screening in never-smokers a game-changer in lung cancer

a day ago

Preworkout dietary supplement use in young people linked to shorter sleep

a day ago

Adolescents and young adults who use preworkout dietary supplements are sleeping an average of not more than 5 h every night, as shown in a study.

Preworkout dietary supplement use in young people linked to shorter sleep

a day ago

GLP-1RAs may offer histologic benefits in adults with MASH

a day ago by

Among adults with biopsy-confirmed metabolic dysfunction-associated steatohepatitis (MASH), treatment with glucagon-like peptide 1 receptor agonists (GLP-1RAs), particularly semaglutide or liraglutide, is associated with higher rates of MASH resolution without worsening of fibrosis compared with placebo, according to a recent Singapore study.

GLP-1RAs may offer histologic benefits in adults with MASH

a day ago

BP-lowering via RAAS inhibition delivers better outcomes in paediatric CKD

a day ago by

In the management of hypertension in paediatric chronic kidney disease (CKD), renin-angiotensin-aldosterone system inhibition (RAASi) is associated with better kidney function preservation and blood pressure control compared with calcium channel blockade, according to a real-world comparative-effectiveness study.