News &amp; Updates

Which antibiotic regimen is best for paediatric appendicitis?

21 Sep 2025 by

The use of antibiotics to treat paediatric appendicitis should target Escherichia coli and anaerobes, suggests a study. Two other bacteria are also present in about a fourth of the cultures, namely viridans group streptococci (VGS) and pseudomonas.

Which antibiotic regimen is best for paediatric appendicitis?

Dotinurad bests febuxostat for Chinese patients with gout

In the treatment of Chinese patients with gout, the use of dotinurad results in a higher response rate compared with febuxostat, according to a phase III study.

Dotinurad bests febuxostat for Chinese patients with gout

No link between IBD treatment and breast cancer

Medications used to treat inflammatory bowel disease (IBD) do not contribute to an increase in the risk of breast cancer, according to a retrospective study.

No link between IBD treatment and breast cancer

5-HTP daily boosts cognitive health in older Singaporeans

20 Sep 2025 by

Daily supplementation with 5-hydroxytryptophan (5-HTP) appears to confer cognitive benefits and reduce depression symptoms in older adults in Singapore, according to a study.

5-HTP daily boosts cognitive health in older Singaporeans

Amlodipine-telmisartan-chlorthalidone combo promises better BP-lowering effect

20 Sep 2025 by

A low-dose combination therapy, AD-209, that includes telmisartan 20 mg, amlodipine 2.5 mg, and chlorthalidone 6.25 mg demonstrates efficacy in lowering high blood pressure (BP) when compared with telmisartan alone in patients with essential hypertension, reports a study presented at ESC 2025.

Amlodipine-telmisartan-chlorthalidone combo promises better BP-lowering effect

20 Sep 2025

Childhood loneliness may have enduring consequences on cognitive health

Childhood loneliness appears to contribute to an increased risk of cognitive decline and dementia in middle and later adulthood, even in the absence of adult loneliness, according to a study.

Childhood loneliness may have enduring consequences on cognitive health

Beta-blockers efficacious in myocardial infarction with mildly reduced LVEF

In the treatment of patients with myocardial infarction (MI) with mildly reduced left ventricular ejection fraction (LVEF), beta-blockers appear to cut the risk of mortality, new MI, and heart failure, according to a study.

Beta-blockers efficacious in myocardial infarction with mildly reduced LVEF

Aerobic exercise benefits individuals with cerebellar ataxia

19 Sep 2025 by

High-intensity aerobic training appears to be a better way to manage cerebellar ataxia than balance training, with favourable effects on symptoms, fatigue, and cardiorespiratory fitness seen in a randomized clinical trial.

Aerobic exercise benefits individuals with cerebellar ataxia

Empirical dietary index predicts risk of gout

A replicated empirical index predicting lower plasma urate shows a significant association with reduced risks of gout and related cardiometabolic conditions, reports a study.

Empirical dietary index predicts risk of gout