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Novel GLP-1/GIP formula finishes strong in phase II obesity, T2D trial
In part 1 (dose ranging with and without dose escalation) of the phase II MariTide study, significant weight reduction and robust glycaemic improvement were achieved with maridebart cafraglutide (MariTide) – the first, long-acting, GIPR* antagonist and GLP-1R** agonist – in individuals with obesity or overweight and type 2 diabetes (T2D).
Novel GLP-1/GIP formula finishes strong in phase II obesity, T2D trial
30 Jun 2025
Tocilizumab with or without MTX for acute RA: Does combo work better than mono?
Subcutaneous tocilizumab, used either as a monotherapy or in combination with methotrexate (MTX), shows greater efficacy than MTX alone in Chinese patients with active rheumatoid arthritis (RA) who have not adequately responded to conventional synthetic disease-modifying antirheumatic drugs (csDMARDs).
Tocilizumab with or without MTX for acute RA: Does combo work better than mono?
27 Jun 2025
MOSAIC updates: MRI outcomes bolster apremilast role in PsA dactylitis
Apremilast, an oral immunomodulating phosphodiesterase-4 inhibitor, reduces inflammation in individual joints and clinical dactylitis as per MRI in patients with psoriatic arthritis (PsA), according to the results of a dynamic contrast-enhanced MRI (DCE-MRI) analysis of the phase IV, open-label MOSAIC study.