News &amp; Updates

In patients with stable inflammatory bowel disease (IBD) receiving advanced therapies who have comorbid obesity and/or diabetes, adjunctive treatment with the glucagon-like peptide-1 receptor agonist (GLP-1 RA) semaglutide or tirzepatide does not appear to improve clinical outcomes, according to new research.

Adjunctive GLP-1 RA treatment of limited benefit in stable IBD patients with obesity, diabetes

Chemo-free regimen a potential new standard of care in paediatric APL

In children with newly diagnosed acute promyelocytic leukaemia (APL), the use of a chemotherapy-free treatment protocol is safe and efficacious, according to the early final results of the ICC-APL-02 study.

Chemo-free regimen a potential new standard of care in paediatric APL

Anti-interleukin-5 monoclonal antibody for asthma passes phase 1 trial

A novel long-acting anti-interleukin-5 monoclonal antibody, SHR-1703, demonstrates promising efficacy with good tolerability in patients with eosinophilic asthma, according to a phase 1 study.

Anti-interleukin-5 monoclonal antibody for asthma passes phase 1 trial

Novel factor B inhibitor superior to eculizumab in paroxysmal nocturnal haemoglobinuria

Treatment with the factor B inhibitor HSK39297 is more efficacious than eculizumab for the management of paroxysmal nocturnal haemoglobinuria (PNH), with no serious safety concerns, suggests a study presented at EHA 2026.

Novel factor B inhibitor superior to eculizumab in paroxysmal nocturnal haemoglobinuria

Denosumab superior to alendronate for BMD loss prevention in malignant lymphoma

The use of denosumab demonstrates superior protection against bone mineral density (BMD) loss at 12 months compared with alendronate in older patients with newly diagnosed lymphoma receiving R-CHOP* and related regimens, as shown in the DENOSULY study.

Denosumab superior to alendronate for BMD loss prevention in malignant lymphoma

01 Jul 2026

Traditional photoscreener retains upper hand for detecting eye disorders in kids

A diagnostic accuracy study shows greater overall diagnostic sensitivity with a traditional autorefraction device than with a newer, distinct photoscreening device—a retinal birefringence scanner (RBS)—for detecting amblyopia and refractive errors in children.

Traditional photoscreener retains upper hand for detecting eye disorders in kids

Exercise performance in obstructive HCM better with aficamten vs metoprolol

In the treatment of patients with obstructive hypertrophic cardiomyopathy (HCM), aficamten exerts superior effects on a broad array of exercise measures compared with metoprolol, according to a secondary analysis of the phase III MAPLE-HCM trial.

Exercise performance in obstructive HCM better with aficamten vs metoprolol

Norucholic acid, with or without UDCA, prevents PSC progression

Patients with primary sclerosing cholangitis (PSC) who received norucholic acid (NCA), with or without ursodeoxycholic acid (UDCA) background therapy, were more likely to achieve histological and biochemical improvements than those receiving placebo, according to the subgroup analysis of the NUC-5 trial presented at EASL 2026.

Norucholic acid, with or without UDCA, prevents PSC progression

Atopic dermatitis does not influence academic performance

Atopic dermatitis (AD) is unlikely to be associated with reduced academic performance among teens taking national compulsory examinations, according to a study.

Atopic dermatitis does not influence academic performance

Cenobamate for epilepsy effective across multiple treatment lines

The use of cenobamate across different treatment lines proves effective at reducing seizures in patients with epilepsy, according to real-world data.

Cenobamate for epilepsy effective across multiple treatment lines