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Liraglutide boosts lipid metabolism in T2DM, but comes with more side effects

02 Sep 2022

Compared with dapagliflozin, the glucagon-like peptide 1 liraglutide induces better lipid metabolism in patients with type 2 diabetes mellitus (T2DM), a recent study has found. However, this drug also comes with more adverse events than its sodium-glucose co-transporter 2 inhibitor comparator.

Liraglutide boosts lipid metabolism in T2DM, but comes with more side effects

02 Sep 2022

Rapid macular thinning predicts hydroxychloroquine retinal toxicity

02 Sep 2022

In many patients receiving long-term hydroxychloroquine therapy, retinal thickness remains stable for years but may start to thin quickly after a critical point, according to a recent study.

Rapid macular thinning predicts hydroxychloroquine retinal toxicity

02 Sep 2022

Could tixagevimab–cilgavimab prevent progression to severe COVID-19 in unvaccinated adults?

01 Sep 2022 by

The combination of tixagevimab and cilgavimab, two SARS-CoV-2 neutralizing monoclonal antibodies, appeared to protect against progression to severe disease or death in non-hospitalized, unvaccinated adults presenting with mild-to-moderate COVID-19, results of the ongoing phase III TACKLE trial showed.

Could tixagevimab–cilgavimab prevent progression to severe COVID-19 in unvaccinated adults?

01 Sep 2022

Fixed-dose pitavastatin–ezetimibe combo bests monotherapy for lowering cholesterol

01 Sep 2022

In the treatment of patients with hypercholesterolaemia, the fixed-dose combination of pitavastatin plus ezetimibe, 1PC111, affords better low-density lipoprotein cholesterol (LDL-C)-lowering effect than either pitavastatin or ezetimibe alone, according to the results of a phase III trial.

Fixed-dose pitavastatin–ezetimibe combo bests monotherapy for lowering cholesterol

01 Sep 2022

Dual therapy as good as triple therapy for treatment-naïve HIV

31 Aug 2022 by

Dual therapy with the fixed-dose combination of darunavir/ritonavir plus lamivudine effectively controlled HIV as the same combination with tenofovir in treatment-naïve patients with HIV, according to the phase IV ANDES trial presented at AIDS 2022.

Dual therapy as good as triple therapy for treatment-naïve HIV

31 Aug 2022

What are the risk factors for infection following vaginal delivery?

30 Aug 2022

The risk of developing infection following operative vaginal birth is high when episiotomy is performed, forceps are used, and among women who are primiparous and overweight, a study has found. As such, timely prophylactic antibiotics should be given.

What are the risk factors for infection following vaginal delivery?

30 Aug 2022

Granisetron prophylaxis does not affect myometrial contraction during caesarean birth

30 Aug 2022

When administered concomitantly with oxytocin, prophylactic granisetron appears to have no negative impact on myometrial contraction during caesarean delivery, reports a recent study.

Granisetron prophylaxis does not affect myometrial contraction during caesarean birth

30 Aug 2022

Early diagnosis and treatment of transthyretin amyloid cardiomyopathy significantly improves outcomes

30 Aug 2022 by

Transthyretin amyloid cardiomyopathy (ATTR-CM) is a significantly underdiagnosed, life-threatening disease caused by the deposition of transthyretin amyloid fibrils in the heart. Dr Soon Chao Yang, Interventional Cardiologist at The Heart Doctors Clinic in Mount Alvernia Hospital, Singapore, reviews the data on early treatment of ATTR-CM, and shares his clinical experience with tafamidis.

Early diagnosis and treatment of transthyretin amyloid cardiomyopathy significantly improves outcomes

30 Aug 2022

Second-line NIVO + IPI combo sustains response, OS benefit in aHCC

30 Aug 2022 by

The combination of nivolumab 1 mg/kg (NIVO1) and ipilimumab 3 mg/kg (IPI3) every 3 weeks followed by NIVO 240 mg every 2 weeks in the second-line setting continues to confer durable response and overall survival (OS) benefit in patients with advanced hepatocellular carcinoma (aHCC), according to 5-year data from the CheckMate 040* trial presented at ESMO GI 2022.

Second-line NIVO + IPI combo sustains response, OS benefit in aHCC

30 Aug 2022

Revacept works in patients with internal carotid artery stenosis

29 Aug 2022

Treatment with revacept 120 mg appears to be beneficial in the treatment of patients with symptomatic internal carotid artery stenosis, according to a study.

Revacept works in patients with internal carotid artery stenosis

29 Aug 2022

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Liraglutide boosts lipid metabolism in T2DM, but comes with more side effects

Liraglutide boosts lipid metabolism in T2DM, but comes with more side effects

Rapid macular thinning predicts hydroxychloroquine retinal toxicity

Rapid macular thinning predicts hydroxychloroquine retinal toxicity

Could tixagevimab–cilgavimab prevent progression to severe COVID-19 in unvaccinated adults?

Could tixagevimab–cilgavimab prevent progression to severe COVID-19 in unvaccinated adults?

Fixed-dose pitavastatin–ezetimibe combo bests monotherapy for lowering cholesterol

Fixed-dose pitavastatin–ezetimibe combo bests monotherapy for lowering cholesterol

Dual therapy as good as triple therapy for treatment-naïve HIV

Dual therapy as good as triple therapy for treatment-naïve HIV

What are the risk factors for infection following vaginal delivery?

What are the risk factors for infection following vaginal delivery?

Granisetron prophylaxis does not affect myometrial contraction during caesarean birth

Granisetron prophylaxis does not affect myometrial contraction during caesarean birth

Early diagnosis and treatment of transthyretin amyloid cardiomyopathy significantly improves outcomes

Early diagnosis and treatment of transthyretin amyloid cardiomyopathy significantly improves outcomes

Second-line NIVO + IPI combo sustains response, OS benefit in aHCC

Second-line NIVO + IPI combo sustains response, OS benefit in aHCC

Revacept works in patients with internal carotid artery stenosis

Revacept works in patients with internal carotid artery stenosis