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ZUMA studies boost therapeutic potential of brexu-cel in R/R MCL

09 Jan 2024 by

In the primary analysis of the expanded-access ZUMA-18 trial, the autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy brexucabtagene autoleucel (brexu-cel) demonstrated a high level of efficacy in patients with relapsed/refractory mantle cell lymphoma (R/R MCL).

ZUMA studies boost therapeutic potential of brexu-cel in R/R MCL

09 Jan 2024

PPI use beneficial to Asian AF patients on direct oral anticoagulant

09 Jan 2024

Proton pump inhibitor (PPI) co-therapy appears to lower the risk of hospitalization for upper gastrointestinal bleeding (UGIB) in atrial fibrillation (AF) patients receiving direct oral anticoagulant (DOAC) treatment, according to a study from Korea.

PPI use beneficial to Asian AF patients on direct oral anticoagulant

09 Jan 2024

Adjuvant alectinib benefits Asians with resected ALK+ NSCLC

09 Jan 2024 by

Adjuvant treatment with alectinib, an anaplastic lymphoma kinase (ALK) inhibitor, significantly improved disease-free survival (DFS) better than platinum-based chemotherapy at 2 years in Asian patients with early-stage, completely resected ALK-positive non–small cell lung cancer (ALK+ NSCLC) in an exploratory analysis of the phase III ALINA trial.

Adjuvant alectinib benefits Asians with resected ALK+ NSCLC

09 Jan 2024

mRNA boosters protect cancer patients against adverse COVID-19 outcomes

08 Jan 2024 by

A prospective study from Singapore provides evidence of the clinical effectiveness of mRNA-based vaccines against COVID-19 in individuals with cancer.

mRNA boosters protect cancer patients against adverse COVID-19 outcomes

08 Jan 2024

AI tools to improve endoscopic training in early-stage GI cancer management

08 Jan 2024 by

Researchers from the Chinese University of Hong Kong (CUHK) have demonstrated the potential application of two artificial intelligence (AI) tools, ENDO-AID and AI-Endo, for training endoscopists in early-stage gastrointestinal (GI) cancer management.

AI tools to improve endoscopic training in early-stage GI cancer management

08 Jan 2024

Fewer nosebleeds with pomalidomide for HHT

08 Jan 2024 by

Daily treatment with the immunomodulatory agent pomalidomide for 6 months significantly reduced severe nosebleeds in patients with hereditary haemorrhagic telangiectasia (HHT) in the double-blind, randomized, placebo-controlled PATH-HHT trial.

Fewer nosebleeds with pomalidomide for HHT

08 Jan 2024

Alzheimer's disease medications may protect against AMD

07 Jan 2024

Older adults with Alzheimer's disease who are receiving treatment with acetylcholinesterase inhibitors (AChEIs) appears to have a small reduction in the risk of age-related macular degeneration (AMD), as reported in a study.

Alzheimer's disease medications may protect against AMD

07 Jan 2024

Biosensors detect aggression risk in young psychiatric inpatients with autism

07 Jan 2024 by

Wearable biosensors and machine learning algorithms show promise in predicting impending aggressive behaviour in youths with autism who are undergoing psychiatric treatment, offering opportunities for intervention and prevention.

Biosensors detect aggression risk in young psychiatric inpatients with autism

07 Jan 2024

Higher folic acid levels during pregnancy may help prevent Kawasaki disease in newborns

07 Jan 2024

Having greater serum folic acid levels and taking folic acid supplements more than once a week during the second and third trimesters appear to lower the risk of Kawasaki disease among infants, according to a study.

Higher folic acid levels during pregnancy may help prevent Kawasaki disease in newborns

07 Jan 2024

Navigating invasive fungal infections in unconventional hosts — insights and strategies

06 Jan 2024 by

At a recent symposium organized by Pfizer, in collaboration with the Society of Infectious Disease Singapore, A/Prof Carolina García-Vidal, Senior Specialist, Infectious Diseases Department at Hospital Clínic de Barcelona, Spain, shared valuable insights on managing invasive fungal infections (IFIs) in nontraditional hosts. The session was chaired by Dr Jasmine Chung, Senior Consultant and Director of the Antimicrobial Stewardship Unit, Singapore General Hospital.

Navigating invasive fungal infections in unconventional hosts — insights and strategies

06 Jan 2024

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ZUMA studies boost therapeutic potential of brexu-cel in R/R MCL

ZUMA studies boost therapeutic potential of brexu-cel in R/R MCL

PPI use beneficial to Asian AF patients on direct oral anticoagulant

PPI use beneficial to Asian AF patients on direct oral anticoagulant

Adjuvant alectinib benefits Asians with resected ALK+ NSCLC

Adjuvant alectinib benefits Asians with resected ALK+ NSCLC

mRNA boosters protect cancer patients against adverse COVID-19 outcomes

mRNA boosters protect cancer patients against adverse COVID-19 outcomes

AI tools to improve endoscopic training in early-stage GI cancer management

AI tools to improve endoscopic training in early-stage GI cancer management

Fewer nosebleeds with pomalidomide for HHT

Fewer nosebleeds with pomalidomide for HHT

Alzheimer's disease medications may protect against AMD

Alzheimer's disease medications may protect against AMD

Biosensors detect aggression risk in young psychiatric inpatients with autism

Biosensors detect aggression risk in young psychiatric inpatients with autism

Higher folic acid levels during pregnancy may help prevent Kawasaki disease in newborns

Higher folic acid levels during pregnancy may help prevent Kawasaki disease in newborns

Navigating invasive fungal infections in unconventional hosts — insights and strategies

Navigating invasive fungal infections in unconventional hosts — insights and strategies