News & Updates
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Tailored therapy reduces antibiotic use in infective endocarditis
A response-tailored strategy decreases antibiotic duration by 2 weeks compared with standard therapy in patients with left-sided infective endocarditis, without compromising their safety. This is the primary result of the POET-II study presented at ESC Congress 2026.
Add-on tafasitamab–lenalidomide improves PFS in BCLs
In the global phase III frontMIND study, adding tafasitamab and lenalidomide (Tafa-Len) to an R-CHOP* chemotherapy regimen significantly improves progression-free survival in patients with previously untreated high-risk diffuse large B-cell lymphoma (DLBCL) and high-grade BCL (HGBCL).
Tebentafusp delivers 5-year survival benefit in metastatic uveal melanoma
Long-term survival benefits with tebentafusp persist in previously untreated HLA-A∗02:01-positive patients with unresectable or metastatic uveal melanoma (mUM), as shown in the longest survival follow-up of a phase III trial.
Lorlatinib delivers long-term survival benefits in advanced ALK-positive NSCLC
First-line treatment with lorlatinib demonstrates long-term survival benefits in patients with advanced anaplastic lymphoma kinase (ALK)-positive nonsmall cell lung cancer (NSCLC), as shown in the 7-year update from the phase III CROWN study.
Nose-only swabs a viable alternative to nose + throat swabs for flu and SARS-CoV-2 detection
According to an outpatient surveillance study in Hong Kong, minimally invasive nose-only swabs achieved high agreement with joint nose and throat swabs (NTS) for reverse transcription polymerase chain reaction (RT-qPCR) detection of influenza and SARS-CoV-2, thus presenting a viable alternative specimen type for supervised respiratory virus testing.