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High-resolution anorectal manometry detects HD in children ≤2 years old

30 May 2024 by

High-resolution anorectal manometry (HR‐ARM) can be a noninvasive primary screening tool for Hirschsprung’s disease (HD), particularly in children ≤2 years old, as shown in a comprehensive retrospective analysis.

High-resolution anorectal manometry detects HD in children ≤2 years old

30 May 2024

48-week data ASSERT odevixibat’s role in ALGS

29 May 2024 by

Pooled analysis of the ASSERT and ASSERT-EXT studies show sustained improvements in multiple parameters with odevixibat in individuals with Alagille syndrome (ALGS), thus reinforcing its role in the treatment of this multisystem genetic disorder.

48-week data ASSERT odevixibat’s role in ALGS

29 May 2024

Dupilumab sustains histological remission in children with EoE

29 May 2024 by

Treatment with higher-dose dupilumab results in sustained improvements in histologic and endoscopic measures of eosinophilic esophagitis (EoE) in children, regardless of prior use of swallowed topical corticosteroids (STCs), according to a subanalysis presented at ESPGHAN 2024.

Dupilumab sustains histological remission in children with EoE

29 May 2024

Achieving remission possible with ustekinumab dose intensification in certain IBD patients

26 May 2024 by

Two-thirds of patients with IBD treated at an IBD centre in Singapore required dose intensification (DI) while on ustekinumab, with over one-third of them achieving disease remission at 1 year, as shown in a retrospective observational study

Achieving remission possible with ustekinumab dose intensification in certain IBD patients

26 May 2024

IBD patients undergoing colectomy at high risk of kidney complications

23 May 2024

The rates of acute kidney injury (AKI) and kidney failure appear to rise following colectomy, especially total colectomy or colectomy with a prolonged stroma, in patients with inflammatory bowel disease (IBD), according to a nationwide Swedish cohort study.

IBD patients undergoing colectomy at high risk of kidney complications

23 May 2024

Mum’s infection during pregnancy may raise newborn’s risk of IBD

23 May 2024 by

Exposure to any infection during early pregnancy or to a gastrointestinal infection during late pregnancy contributes to the increased likelihood of inflammatory bowel disease (IBD) development, especially Crohn’s disease, in the offspring, according to a study.

Mum’s infection during pregnancy may raise newborn’s risk of IBD

23 May 2024

Children, teens with EoE respond to budesonide oral suspension

22 May 2024 by

Budesonide oral suspension is well tolerated and superior to placebo at inducing remission in paediatric patients with eosinophilic esophagitis (EoE), with the high-dose formulation offering the best results, according to the results of the phase II/III PEDEOS-1 trial.

Children, teens with EoE respond to budesonide oral suspension

22 May 2024

Fibre intake may prevent celiac disease in first 2 years of life

22 May 2024 by

Increased intake of dietary fibre at age 2 years and below tends to reduce the risks for celiac disease (CD) and celiac disease autoimmunity (CDA) in genetically at-risk children, suggests a study presented at the recent ESPGHAN 2024.

Fibre intake may prevent celiac disease in first 2 years of life

22 May 2024

Ultra-processed foods linked to constipation

22 May 2024

Eating more ultra-processed foods leads to constipation, whereas greater consumption of minimally processed foods has the opposite effect, according to a cross-sectional study.

Ultra-processed foods linked to constipation

22 May 2024

Immune-mediated gut problems tied to eating disorders

21 May 2024 by

People with immune-mediated gastrointestinal (GI) disease, especially children, are more prone to eating disorders, as shown in a study.

Immune-mediated gut problems tied to eating disorders

21 May 2024

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High-resolution anorectal manometry detects HD in children ≤2 years old

High-resolution anorectal manometry detects HD in children ≤2 years old

48-week data ASSERT odevixibat’s role in ALGS

48-week data ASSERT odevixibat’s role in ALGS

Dupilumab sustains histological remission in children with EoE

Dupilumab sustains histological remission in children with EoE

Achieving remission possible with ustekinumab dose intensification in certain IBD patients

Achieving remission possible with ustekinumab dose intensification in certain IBD patients

IBD patients undergoing colectomy at high risk of kidney complications

IBD patients undergoing colectomy at high risk of kidney complications

Mum’s infection during pregnancy may raise newborn’s risk of IBD

Mum’s infection during pregnancy may raise newborn’s risk of IBD

Children, teens with EoE respond to budesonide oral suspension

Children, teens with EoE respond to budesonide oral suspension

Fibre intake may prevent celiac disease in first 2 years of life

Fibre intake may prevent celiac disease in first 2 years of life

Ultra-processed foods linked to constipation

Ultra-processed foods linked to constipation

Immune-mediated gut problems tied to eating disorders

Immune-mediated gut problems tied to eating disorders