News & Updates

4F-PCC safe, effective in factor Xa inhibitor-related bleedings

Treatment with four-factor prothrombin complex concentrate (4F-PCC) appears safe and effective for patients with factor Xa inhibitor-associated bleeding events, suggests a recent study.

Apremilast provides skin clearance in paediatric psoriasis

Treatment with apremilast showed clear or almost clear skin in paediatric patients with moderate-to-severe plaque psoriasis, according to the SPROUT study presented at AAD 2023.

COVID-19 vaccine-induced immunity PROTECTS BETTER than natural immunity from previous infection

Vaccination against COVID-19 provides superior protection against all-cause health events as shown in a recent study in the US. Vaccinated individuals had significantly lower all-cause mortality, hospitalization, and emergency department visits than those who were previously infected but were unvaccinated.

This suggests that strong natural immunity acquired from a previous COVID-19 infection does not appear to fully compensate for the detrimental effects of an initial infection.

Focused ultrasound ablation improves motor function in Parkinson’s

Patients with Parkinson’s disease (PD) who have undergone unilateral focused ultrasound ablation of the internal segment of globus pallidus show improved motor function or reduced dyskinesia over a period of 3 months, although the procedure comes with adverse events, according to a study.

Medicare Advantage affects readmission/mortality ranking of top-performing hospitals

A US study reports about one in four top-performing hospitals being reclassified to a lower performance group when Medicare Advantage (MA) beneficiaries are included in the assessment of hospital readmission and mortality.

Second-line bevacizumab plus irinotecan extends survival in glioblastoma

The combination of bevacizumab and irinotecan (BEV+IRI) as second-line treatment of glioblastoma (GBM) results in better median progression-free (PFS) and overall survival (OS) when compared with historical controls, and its toxicity profile is comparable to published data, reports a study.

Cardiac arrest not uncommon during delivery hospitalization

One cardiac arrest occurs for every 9,000 delivery hospitalizations, among which about seven in 10 women survive to be discharged from the hospital, according to a study. In addition, survival is lowest during hospitalizations with co-occurring disseminated intravascular coagulation (DIC).

Vitamin D supplementation of little help in reducing psoriasis severity

Among individuals with psoriasis, oral vitamin D supplementation does not appear to have any favourable effect on disease severity for those with low 25-hydroxyvitamin D (25[OH]D) levels, as reported in a study.