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Aspiration pneumonia outcomes better with ampicillin–sulbactam vs cephalosporins

05 Aug 2025

In the treatment of patients with aspiration pneumonia, ampicillin–sulbactam helps reduce in-hospital mortality and prevent Clostridioides difficile infection compared with cephalosporins, according to a study from Japan.

Aspiration pneumonia outcomes better with ampicillin–sulbactam vs cephalosporins

05 Aug 2025

Clomiphene citrate ups chances of multiple pregnancy, perinatal complications

04 Aug 2025 by

Women exposed to clomiphene citrate (CC) have fourfold greater odds of becoming pregnant with multiples, and this seems to come with adverse perinatal outcomes, as shown in a French cohort study.

Clomiphene citrate ups chances of multiple pregnancy, perinatal complications

04 Aug 2025

Weekly fixed-dosed efsitora as good as daily glargine in T2D

04 Aug 2025

For adult patients with type 2 diabetes (T2D) who are naïve to insulin, a once-weekly fixed-dose efsitora regimen is noninferior to once-daily glargine at reducing blood glucose levels, according to the phase III treat-to-target QWINT-1 trial.

Weekly fixed-dosed efsitora as good as daily glargine in T2D

04 Aug 2025

Nirmatrelvir–ritonavir combo not better than ritonavir alone in adults with long COVID

03 Aug 2025

For individuals with long COVID, treatment with nirmatrelvir plus ritonavir does not appear to yield improvements in health outcomes when compared with ritonavir alone, according to a phase II study.

Nirmatrelvir–ritonavir combo not better than ritonavir alone in adults with long COVID

03 Aug 2025

No excess liver cancer risk seen with oral contraceptive use

03 Aug 2025 by

Two large prospective cohorts show no evidence of an association between the use of oral contraceptives and the risk of liver cancer.

No excess liver cancer risk seen with oral contraceptive use

03 Aug 2025

Higher superior to low atropine dose, orthokeratology for paediatric myopia

03 Aug 2025

Treatment with 0.04% atropine appears to improve myopia control in children and teens compared with 0.01% atropine or orthokeratology, despite a higher incidence of photophobia, according to a study.

Higher superior to low atropine dose, orthokeratology for paediatric myopia

03 Aug 2025

Risk of MACE higher with sulfonylureas vs DPP4is

02 Aug 2025

In the treatment of patients with type 2 diabetes, sulfonylureas pose an increased risk of major adverse cardiovascular events (MACE) compared with dipeptidyl peptidase 4 inhibitors (DPP4is), according to a study.

Risk of MACE higher with sulfonylureas vs DPP4is

02 Aug 2025

Bimekizumab shows long-term benefits across axSpA spectrum

02 Aug 2025 by

Treatment with bimekizumab showed sustained efficacy for up to 3 years in patients with nonradiographic (nr) and radiographic (r) axial spondyloarthritis (axSpA), based on a pooled analysis of the two phase III studies (BE MOBILE 1 and 2) and combined open-label extension (OLE) study presented at EULAR 2025.

Bimekizumab shows long-term benefits across axSpA spectrum

02 Aug 2025

Polypharmacy, inappropriate medications common in older cancer patients

31 Jul 2025

Older patients with cancer are unusually susceptible to polypharmacy, as well as potentially inappropriate medications and potential drug-drug interactions, reveals a study.

Polypharmacy, inappropriate medications common in older cancer patients

31 Jul 2025

Thiazolidinedione reduces mortality, adverse events in T2D patients with AKD

31 Jul 2025

Treatment with thiazolidinedione (TZD) results in a significant decrease in mortality, cardiovascular events, and kidney-related adverse events among type 2 diabetes (T2D) patients with acute kidney disease (AKD), a recent study has shown.

Thiazolidinedione reduces mortality, adverse events in T2D patients with AKD

31 Jul 2025

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Aspiration pneumonia outcomes better with ampicillin–sulbactam vs cephalosporins

Aspiration pneumonia outcomes better with ampicillin–sulbactam vs cephalosporins

Clomiphene citrate ups chances of multiple pregnancy, perinatal complications

Clomiphene citrate ups chances of multiple pregnancy, perinatal complications

Weekly fixed-dosed efsitora as good as daily glargine in T2D

Weekly fixed-dosed efsitora as good as daily glargine in T2D

Nirmatrelvir–ritonavir combo not better than ritonavir alone in adults with long COVID

Nirmatrelvir–ritonavir combo not better than ritonavir alone in adults with long COVID

No excess liver cancer risk seen with oral contraceptive use

No excess liver cancer risk seen with oral contraceptive use

Higher superior to low atropine dose, orthokeratology for paediatric myopia

Higher superior to low atropine dose, orthokeratology for paediatric myopia

Risk of MACE higher with sulfonylureas vs DPP4is

Risk of MACE higher with sulfonylureas vs DPP4is

Bimekizumab shows long-term benefits across axSpA spectrum

Bimekizumab shows long-term benefits across axSpA spectrum

Polypharmacy, inappropriate medications common in older cancer patients

Polypharmacy, inappropriate medications common in older cancer patients

Thiazolidinedione reduces mortality, adverse events in T2D patients with AKD

Thiazolidinedione reduces mortality, adverse events in T2D patients with AKD