Oral mitapivat beneficial in the treatment of non-transfusion-dependent thalassaemia
Mitapivat, an oral activator of pyruvate kinase, appears to increase haemoglobin concentration and improve fatigue in adults with non-transfusion-dependent (NTD) α-thalassaemia or NTD β-thalassaemia, according to the double-blind phase III ENERGIZE study.