News &amp; Updates

The association between triglyceride-glucose (TyG) index and emotional states is stronger in women than in men, suggests a study.

TyG index tied to emotional well-being in women with hypertension

FLAURA2 regimen achieves median OS of nearly 4 years in EGFR-mutated advanced NSCLC

First-line osimertinib plus chemotherapy demonstrated a median overall survival (mOS) of nearly 4 years in patients with EGFR-mutated (exon 19 deletion or L858R mutation) advanced non-small-cell lung cancer (NSCLC) in the final OS analysis of the FLAURA 2 trial.

FLAURA2 regimen achieves median OS of nearly 4 years in EGFR-mutated advanced NSCLC

First phase III results show PFS benefit with pirtobrutinib vs BR in treatment-naïve CLL/SLL

Single-agent pirtobrutinib significantly improved progression-free survival (PFS) vs bendamustine plus rituximab (BR) for patients with treatment-naïve chronic lymphocytic leukaemia/small lymphocytic lymphoma (CLL/SLL), according to the first results from the phase III BRUIN CLL-313 trial.

First phase III results show PFS benefit with pirtobrutinib vs BR in treatment-naïve CLL/SLL

22 Jan 2026

SGLT2i may delay hormone therapy failure in prostate cancer

Intention-to-treat (ITT) SGLT2 inhibitor (SGLTi) use was associated with reduced risk of androgen deprivation therapy (ADT) and androgen receptor pathway inhibitor (APRI) failure, according to findings of a population-based study in Hong Kong.

SGLT2i may delay hormone therapy failure in prostate cancer

Nonadherence to PAH medications compromises outcomes

Patients with pulmonary arterial hypertension (PAH) who do not adhere to medications appear to have poor clinical outcomes, according to a study.

Nonadherence to PAH medications compromises outcomes

Inpatient rehab improves post-stroke upper limb function

Stroke survivors who underwent inpatient rehabilitation experienced significant improvements in upper extremity (UE) impairment and in related UE-dependent activities of daily living (ADL), according to a recent study in Singapore.

Inpatient rehab improves post-stroke upper limb function

Prenatal benzodiazepine use poses risk of adverse pregnancy outcomes

The use of benzodiazepine during pregnancy has been associated with elevated risks of preterm birth and small for gestational age in a recent study.

Prenatal benzodiazepine use poses risk of adverse pregnancy outcomes

$Liposomal irinotecan plus nimotuzumab takes on immunotherapy-refractory NPC$

Liposomal irinotecan plus nimotuzumab takes on immunotherapy-refractory NPC

21 Jan 2026 by

In patients with recurrent or metastatic nasopharyngeal carcinoma (NPC) refractory to immune checkpoint inhibitor (ICI) therapy, the combination of liposomal irinotecan plus nimotuzumab yields meaningful clinical activity while having favourable tolerability, as shown in a phase II study.

Liposomal irinotecan plus nimotuzumab takes on immunotherapy-refractory NPC

Biologics may improve synovitis, enthesitis in subclinical PsA patients

Treatment with biologics results in short-term improvements of joint synovitis and enthesitis in patients with subclinical psoriatic arthritis (PsA), specifically for small joint synovitis, a study has shown.

Biologics may improve synovitis, enthesitis in subclinical PsA patients

JSpADA passes disease measure validation for enthesitis-related, juvenile PsA

21 Jan 2026 by

A post hoc analysis of the JUNIPERA study has validated the Juvenile Spondyloarthritis Disease Activity Index (JSpADA) as a disease measure for children with enthesitis-related arthritis (ERA) and juvenile psoriatic arthritis (jPsA) in a prospective clinical trial setting, discriminating between active and inactive disease.

JSpADA passes disease measure validation for enthesitis-related, juvenile PsA