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PM2.5 exposure factors in worsening dementia

16 Sep 2025

New research has linked exposure to fine particulate matter (PM2.5) to a worsening of dementia symptoms and an increase in the brain changes associated with Alzheimer’s disease.

PM2.5 exposure factors in worsening dementia

16 Sep 2025

Partial heart transplant safe, feasible in congenital heart disease

16 Sep 2025

A partial heart transplant appears to be a safe and efficacious approach to replace a faulty heart valve in children with congenital heart disease, as shown in a study.

Partial heart transplant safe, feasible in congenital heart disease

16 Sep 2025

RSV, COVID-19, and pneumococcal disease vaccination updates in Singapore

16 Sep 2025

At the Singapore Thoracic Society (STS) Annual Scientific Meeting 2025, Dr Ian Wee Liang En from the Department of Infectious Diseases/Infection Prevention and Epidemiology, Singapore General Hospital, provided an update on respiratory viral infections and the evolving role of vaccination in reducing disease burden. Dr Wee, who has recently authored several publications on respiratory syncytial virus (RSV), SARS-CoV-2 Omicron, and influenza infections in Singapore, focused his presentation on RSV, with additional updates on COVID-19 and pneumococcal disease.

RSV, COVID-19, and pneumococcal disease vaccination updates in Singapore

16 Sep 2025

Add-on polatuzumab vedotin boosts survival, responses in R/R DLBCL

16 Sep 2025 by

All key survival and response endpoints are met in the phase III POLARGO trial evaluating polatuzumab vedotin plus rituximab and GemOx for patients with R/R DLBCL who are ineligible for stem cell transplant

Add-on polatuzumab vedotin boosts survival, responses in R/R DLBCL

16 Sep 2025

Hydroxychloroquine falls flat for RA prevention in at-risk individuals

15 Sep 2025

Treatment with hydroxychloroquine (HCQ) for 12 months does not appear to prevent the development of rheumatoid arthritis (RA) among at-risk individuals, as shown in a phase II study.

Hydroxychloroquine falls flat for RA prevention in at-risk individuals

15 Sep 2025

ALONE-AF: Safe to stop anticoagulant therapy after AF ablation for recurrence-free patients

15 Sep 2025 by

For individuals without documented recurrence for at least a year following catheter ablation for atrial fibrillation (AF), discontinuing oral anticoagulant therapy results in more favourable outcomes than when continued, according to the ALONE-AF trial.

ALONE-AF: Safe to stop anticoagulant therapy after AF ablation for recurrence-free patients

15 Sep 2025

Better lifestyle choices may prevent cancer in adults with prediabetes, T2D

15 Sep 2025

Alignment with the 2018 World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) Cancer Prevention Recommendations, which involve modifying certain lifestyle factors, appears to reduce the risk of cancer development in adults with prediabetes or type 2 diabetes (T2D), reports a recent study.

Better lifestyle choices may prevent cancer in adults with prediabetes, T2D

15 Sep 2025

$High CRP predicts risk of steroid-refractory ASUC$

High CRP predicts risk of steroid-refractory ASUC

15 Sep 2025 by

An elevated C-reactive protein (CRP) or CRP–albumin ratio on admission is significantly associated with the risk of steroid-refractory disease in patients with acute severe ulcerative colitis (ASUC), suggests a Singapore study.

High CRP predicts risk of steroid-refractory ASUC

15 Sep 2025

Lifestyle mediates link between deprivation, premature death in patients with T2D

15 Sep 2025

Unhealthy lifestyles facilitate the association seen between socioeconomic deprivation and premature mortality in patients with type 2 diabetes (T2D) and result in a disproportionate risk of premature death in more deprived individuals, a study has found.

Lifestyle mediates link between deprivation, premature death in patients with T2D

15 Sep 2025

PORTEC-3: Adjuvant chemoradiotherapy improves 10-year OS in high-risk endometrial cancer

15 Sep 2025 by

Adjuvant chemoradiotherapy (CRT) improves both 10-year overall survival (OS) and recurrence-free survival (RFS) in women with high-risk endometrial cancer vs pelvic radiotherapy alone, with the most clinically relevant benefit observed in p53 abnormal cancers, according to the 10-year analysis of the phase III PORTEC-3 trial.

PORTEC-3: Adjuvant chemoradiotherapy improves 10-year OS in high-risk endometrial cancer

15 Sep 2025

News & Updates

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PM2.5 exposure factors in worsening dementia

PM2.5 exposure factors in worsening dementia

Partial heart transplant safe, feasible in congenital heart disease

Partial heart transplant safe, feasible in congenital heart disease

RSV, COVID-19, and pneumococcal disease vaccination updates in Singapore

RSV, COVID-19, and pneumococcal disease vaccination updates in Singapore

Add-on polatuzumab vedotin boosts survival, responses in R/R DLBCL

Add-on polatuzumab vedotin boosts survival, responses in R/R DLBCL

Hydroxychloroquine falls flat for RA prevention in at-risk individuals

Hydroxychloroquine falls flat for RA prevention in at-risk individuals

ALONE-AF: Safe to stop anticoagulant therapy after AF ablation for recurrence-free patients

ALONE-AF: Safe to stop anticoagulant therapy after AF ablation for recurrence-free patients

Better lifestyle choices may prevent cancer in adults with prediabetes, T2D

Better lifestyle choices may prevent cancer in adults with prediabetes, T2D

High CRP predicts risk of steroid-refractory ASUC

High CRP predicts risk of steroid-refractory ASUC

Lifestyle mediates link between deprivation, premature death in patients with T2D

Lifestyle mediates link between deprivation, premature death in patients with T2D

PORTEC-3: Adjuvant chemoradiotherapy improves 10-year OS in high-risk endometrial cancer

PORTEC-3: Adjuvant chemoradiotherapy improves 10-year OS in high-risk endometrial cancer